Netherton R A, Lee P S, Overstreet D H
Experientia. 1977 Nov 15;33(11):1463-4. doi: 10.1007/BF01918809.
An attempt was made to replicate the conflicting previous reports of hypo- and hyperthermic effects of intrahypothalamically administered carbachol. Despite using the same coordinates, injection parameters, and strain of rats reported by others, only hypothermia was conclusively demonstrated. It was concluded that the cholinergic system mediates heat loss mechanisms in rats.
研究人员试图重复先前关于下丘脑内注射卡巴胆碱产生低温和高温效应的相互矛盾的报告。尽管使用了与其他人报告的相同的坐标、注射参数和大鼠品系,但仅确凿地证明了低温现象。得出的结论是,胆碱能系统介导大鼠的散热机制。