Luo J H, Rotterdam H
Department of Pathology, Columbia-Presbyterian Medical Center, New York, New York 10032, USA.
Mod Pathol. 1997 Jul;10(7):735-8.
We present a case of primary amyloid tumor of the breast. Although isolated amyloidosis of other organs occurs frequently, it is extremely rare in the breast: only seven well-documented cases have been reported. Our case has the additional unusual feature of belonging to the amyloid AA type of amyloid instead of the more common amyloid AL type. Immunohistochemical studies are documented. The clinical and pathologic characteristics of all of the reported cases are tabulated. These cases suggest that primary amyloid tumor in the breast has the following clinicopathologic features: it affects postmenopausal women between the ages of 54 to 82 years (mean, 68 yr), involves the right breast more often than the left (ratio, 3:1), is clinically frequently misdiagnosed as carcinoma, and probably has a diverse pathogenesis.
我们报告一例乳腺原发性淀粉样瘤病例。尽管其他器官的孤立性淀粉样变性病很常见，但在乳腺中极为罕见：仅有7例有充分文献记载的病例被报道。我们的病例还有一个不寻常的特征，即属于淀粉样蛋白AA型而非更常见的淀粉样蛋白AL型。记录了免疫组织化学研究情况。将所有报道病例的临床和病理特征制成表格。这些病例提示，乳腺原发性淀粉样瘤具有以下临床病理特征：它影响54至82岁（平均68岁）的绝经后女性，右侧乳腺受累比左侧更常见（比例为3:1），临床上常被误诊为癌，并且可能有多种发病机制。
