Felder E, Pitrè D, Tirone P
Farmaco Sci. 1977 Nov;32(11):835-44.
L-5-alpha-hydroxypropionylamino-2,4,6-triiodoisophthalic acid di-(1,3-dihydroxy-2-propylamide), abbreviated Iopamidol, a new non-ionic water soluble contrast agent for angiography, myelography, ventriculography and for contrast reinforced computer-assisted axial tomography is described. Extensive preclinical testing showed favorable physico-chemical features of the new compound, low systemic toxicity, excellent cardiovascular and renal tolerability, very mild effects on the blood-brain barrier and on nervous tissue.
L-5-α-羟基丙酰氨基-2,4,6-三碘间苯二甲酸二（1,3-二羟基-2-丙酰胺），简称碘帕醇，是一种用于血管造影、脊髓造影、脑室造影以及增强计算机断层扫描的新型非离子型水溶性造影剂。广泛的临床前试验表明，这种新化合物具有良好的物理化学特性、低全身毒性、出色的心血管和肾脏耐受性，对血脑屏障和神经组织的影响非常轻微。
