Koffa M, Spandidos D A
Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens, Greece.
Ann N Y Acad Sci. 1997 Jun 17;816:347-55. doi: 10.1111/j.1749-6632.1997.tb52160.x.
Cancer is a multistep process resulting in the accumulation of genetic lesions in proto-oncogenes or tumor suppressor genes. In recent years, many biological studies have focused on the analysis of the genetic and molecular events occurring in genital tumors in order to identify genes involved in their initiation and progression. Understanding the genetic events that lead to initiation and progression of a disease remains an important challenge in gynecological research and ultimately may enable the development of better approaches for earlier diagnosis, in cases where current therapeutic strategies have a high cure rate.
