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青春期女性的宫内避孕。吉妮柔适宫内节育器。

Intrauterine contraception in adolescent women. The GyneFix intrauterine implant.

作者信息

Wildemeersch D, Van Kets H, Vrijens M, Delbarge W, Van Trappen Y, Temmerman M, Depypere H, Thiery M

机构信息

Department of Obstetrics and Gynaecology, University of Ghent, Belgium.

出版信息

Ann N Y Acad Sci. 1997 Jun 17;816:440-50. doi: 10.1111/j.1749-6632.1997.tb52174.x.

Abstract

Pregnancy rates among adolescents have not decreased over the last 10 years, despite numerous efforts. To solve this important health problem, the major strategy recommended is to encourage contraceptive use among sexually active teenagers. An important means of obtaining this is by promoting methods that are not dependent on daily administration in order to avoid noncompliance. One such method (Norplant) has already shown to be much more effective than the combination pill in preventing pregnancy in adolescent women. The frameless intrauterine implant system (fixed, frameless, and completely flexible) has been studied since 1985 in women between 14 and 50 years of age. The results in young nulligravid women confirm its very high effectiveness (cumulative pregnancy rate at 36 months: 1.4%), its low expulsion rate (cumulative rate at 36 months: 0.9%) and its optimal tolerance (cumulative removal rate for medical reasons at 36 months: 2.4%), resulting in a high acceptance of the implant and a high continued use. The system (GyneFix) offers long-term protection (5 years), and its insertion, with or without anesthetic, is easily accomplished in the office. The GyneFix should therefore be recommended as an excellent alternative for birth control pills for young women with low risk for STDs, especially when compliance is a problem, without an increased risk for complications and without systemic side effects. Removal of the device is accomplished by traction on the tail. It can also be used for emergency contraception and for insertion immediately after termination of pregnancy.

摘要

尽管付出了诸多努力,但青少年的怀孕率在过去10年中并未下降。为解决这一重要的健康问题,推荐的主要策略是鼓励性活跃的青少年使用避孕措施。实现这一目标的一个重要手段是推广不依赖每日用药的方法,以避免不依从性。一种这样的方法(诺普兰)已被证明在预防青春期女性怀孕方面比复方口服避孕药有效得多。自1985年以来,无支架宫内节育器系统(固定、无支架且完全灵活)已在14至50岁的女性中进行了研究。在年轻未孕女性中的研究结果证实了其极高的有效性(36个月时的累积怀孕率:1.4%)、低脱落率(36个月时的累积率:0.9%)和最佳耐受性(36个月时因医学原因的累积取出率:2.4%),这使得该节育器的接受度高且持续使用率高。该系统(吉妮柔适)提供长期保护(5年),并且无论有无麻醉,其放置都可在门诊轻松完成。因此,对于性传播疾病风险较低的年轻女性,尤其是在存在依从性问题时,吉妮柔适应被推荐为口服避孕药的极佳替代品,且不会增加并发症风险和出现全身副作用。通过牵拉尾丝即可取出该装置。它还可用于紧急避孕以及在妊娠终止后立即放置。

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