[婴儿获得性巨细胞病毒感染。1例用更昔洛韦成功治疗的病例]
[Acquired cytomegalovirus infection in infants. A case successfully treated with ganciclovir].
作者信息
Dündaröz R, Akin R, Okutan V, Sarici U, Alpay F, Gökçay E
机构信息
Service de Pédiatrie, Hôpital de Mevki Asker Hastanesi, Diskapi, Ankara, Turquie.
出版信息
Presse Med. 1997 Jun 21;26(21):1000-1.
BACKGROUND
Congenital cytomegalovirus infection is a severe condition. When acquired after birth prognosis is less severe although sensorial sequelae and risks justify treatment.
CASE REPORT
A 2.5 year old infant with hepatitis due to cytomegalovirus infection acquired after birth was treated with intravenous ganciclovir (7.5 mg/kg b.i.d for 2 weeks then 10 mg/kg three times a week for 2 months. No side effect or toxicity was observed and the patient recovered without sequellae.
DISCUSSION
In our experience, in addition to severe and symptomatic congenital cytomegalovirus infections, ganciclovir can be used in the treatment of less severe symptomatic acquired cytomegalovirus in infants.
背景
先天性巨细胞病毒感染是一种严重的病症。出生后感染，尽管感觉后遗症和风险需要治疗，但预后没那么严重。
病例报告
一名2.5岁因出生后感染巨细胞病毒而患肝炎的婴儿接受了静脉注射更昔洛韦治疗（7.5毫克/千克，每日两次，共2周，然后10毫克/千克，每周三次，共2个月）。未观察到副作用或毒性，患者康复且无后遗症。
讨论
根据我们的经验，除了严重的有症状的先天性巨细胞病毒感染外，更昔洛韦还可用于治疗婴儿不太严重的有症状的后天性巨细胞病毒感染。
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