Yamamoto S, Hirata T, Yamagishi S, Yamashita Y, Hirano S, Kutsukata N, Masuda S, Hisayoshi T, Hioki M
Dept. of Surgery, 2nd Hospital of Nippon Medical School.
Gan To Kagaku Ryoho. 1997 Jul;24(9):1157-60.
We herein present a case of a 70-year-old man with the tentative diagnosis of far-advanced gastric cancer supposed to be beyond surgical intervention. Neoadjuvant chemotherapy enabled us to perform subtotal gastrectomy with curative intent. The man was admitted to our hospital with the chief complaint of poor appetite. Because preoperative examinations revealed a mass adjacent to the portal vein and common bile duct, which was suspected to be lymphnode metastasis or gastric cancer directly invading those vital structures, 4 weeks of neoadjuvant combination chemotherapy (NACC) (CDDP 10 mg/body, day 1 through day 5/week, UFT 600 mg/body, every day, Leucovorin 15 mg/body, every day) was given with resultant curative resection of the tumor one month after completion of NACC.
我们在此报告一例70岁男性患者，初步诊断为晚期胃癌，预计无法进行手术干预。新辅助化疗使我们能够进行具有治愈意图的胃次全切除术。该男子因食欲不佳为主诉入院。由于术前检查发现门静脉和胆总管附近有肿块，怀疑是淋巴结转移或胃癌直接侵犯这些重要结构，因此给予了4周的新辅助联合化疗（NACC）（顺铂10mg/体，第1天至第5天/周，优福定600mg/体，每日，亚叶酸钙15mg/体，每日），NACC完成后1个月肿瘤得以根治性切除。
