Günther B, Vargas V
Departamento de Fisiología y Biofisica, Facultad de Medicina, Hospital Clinico de la Universidad de Chile, Santiago de Chile.
Rev Med Chil. 1996 Oct;124(10):1261-72.
Since Rubner established in 1883 the "surface law", the basal metabolic rate (kcal/24 h) is expressed per square meter of body surface. This so-called biological law has been extrapolated to the standardization of several other functions as, for instance, to variables of the cardiovascular, respiratory and renal systems, which may lead to erroneous conclusions. The present paper is an attempt to establish, by means of the dimensional analysis and one of the theories of biological similarity, an allometric indexation procedure, which yields mass-independent numbers (MIN) for all functions which can be defined by means of the MLT-system of physics (M = mass; L = length; and T = time).
自1883年鲁布纳确立“表面定律”以来,基础代谢率(千卡/24小时)以每平方米体表面积来表示。这条所谓的生物学定律已被外推至其他几种功能的标准化,例如心血管、呼吸和肾脏系统的变量,而这可能会导致错误的结论。本文试图通过量纲分析和一种生物相似性理论来建立一种异速生长指数化程序,该程序能为所有可通过物理学的MLT系统(M = 质量;L = 长度;T = 时间)来定义的功能生成与质量无关的数值(MIN)。