考察福尔得胆碱能缺陷剖面图在日本版韦氏成人智力量表修订版（WAIS-R）上的诊断效用。
Examining the diagnostic utility of the Fuld cholinergic deficit profile on the Japanese WAIS-R.
作者信息
Yamashita H, Hirono N, Ikeda M, Ikejiri Y, Imamura T, Shimomura T, Mori E
机构信息
Department of Clinical Neuroscience, Hyogo Institute for Aging Brain and Cognitive Disorders, Saisho-Ko, Himeji, Japan.
出版信息
J Clin Exp Neuropsychol. 1997 Apr;19(2):300-4. doi: 10.1080/01688639708403859.
The diagnostic utility of the Fuld cholinergic deficit profile (Fuld, 1984) to dementia of the Alzheimer type (DAT) was evaluated on the Japanese version of the WAIS-R. Profiles were calculated for groups of subjects with DAT(n = 236), vascular dementia (n = 29), frontotemporal dementia (n = 22), and hydrocephalic dementia (n = 10). The frequency of positive profile occurrence for the subject groups was as follows: 23/236 for DAT (9.7%), 2/29 (6.9%) for vascular dementia, 2/22 (9.1%) for frontotemporal dementia, and 2/10 (20%) for hydrocephalic dementia. No significant difference in the frequency of positive profile occurrence was revealed across four types of dementia. We conclude from these findings that the Fuld profile lacks the diagnostic utility on the Japanese WAIS-R.
在日本版韦氏成人智力量表修订版（WAIS-R）上，对福尔胆碱能缺陷剖面图（Fuld，1984）在阿尔茨海默型痴呆（DAT）中的诊断效用进行了评估。为患有DAT（n = 236）、血管性痴呆（n = 29）、额颞叶痴呆（n = 22）和脑积水性痴呆（n = 10）的受试者组计算了剖面图。受试者组中阳性剖面图出现的频率如下：DAT为23/236（9.7%），血管性痴呆为2/29（6.9%），额颞叶痴呆为2/22（9.1%），脑积水性痴呆为2/10（20%）。在四种类型的痴呆中，阳性剖面图出现的频率没有显著差异。从这些发现中我们得出结论，福尔剖面图在日本WAIS-R上缺乏诊断效用。
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