韦氏成人智力量表修订版（WAIS-R）中加速衰老和阿尔茨海默病型痴呆的一个标志物？韦氏成人智力量表修订版标准化样本中福尔兹公式的基础比率。

A WAIS-R marker for accelerated aging and dementia, Alzheimer's type? Base rates of the Fuld formula in the WAIS-R standardization sample.

作者信息

Satz P, Hynd G W, D'Elia L, Daniel M H, Van Gorp W, Connor R

机构信息

Neuropsychiatric Institute, University of California, Los Angeles 90024.

出版信息

J Clin Exp Neuropsychol. 1990 Oct;12(5):759-65. doi: 10.1080/01688639008401017.

DOI:10.1080/01688639008401017

PMID:2258435

Abstract

Recent reports have provided evidence that a WAIS-R marker for dementia of the Alzheimer's type (DAT) may have value in differential clinical diagnosis. Using the Fuld (1984) formula, this study investigated the prevalence of the WAIS-R marker in the WAIS-R standardization sample (N = 1,880), whose members range in age from 16 to 74 years. The results from the WAIS-R sample suggest no significant age differences in the occurrence of this marker when age-corrected scaled scores are employed. Across age, the occurrence of this marker is about 6.2%. Although there were no significant effects according to race, there were significant sex (males = 7.34%; females = 5.11%) and education effects. For individuals aged 65-74 with some post high school education, the base rate was about 14%. These findings are discussed as they relate to the potential clinical usefulness of this marker in the differential diagnosis of DAT.

摘要

最近的报告提供了证据，表明韦氏成人智力量表修订版（WAIS-R）中阿尔茨海默病型痴呆（DAT）的一个指标可能在临床鉴别诊断中具有价值。本研究使用富尔德（1984年）的公式，调查了WAIS-R标准化样本（N = 1880）中该WAIS-R指标的患病率，样本成员年龄在16至74岁之间。WAIS-R样本的结果表明，当使用年龄校正后的量表分数时，该指标的出现没有显著的年龄差异。在所有年龄段中，该指标的出现率约为6.2%。虽然按种族没有显著影响，但存在显著的性别（男性 = 7.34%；女性 = 5.11%）和教育程度影响。对于65至74岁且有高中后某种教育程度的个体，基础率约为14%。讨论了这些发现与该指标在DAT鉴别诊断中的潜在临床实用性的关系。