Vercellini P, De Giorgi O, Aimi G, Panazza S, Uglietti A, Crosignani P G
Clinica Ostetrica e Ginecologica Luigi Mangiagalli, University of Milano, Italy.
Obstet Gynecol. 1997 Aug;90(2):264-8. doi: 10.1016/S0029-7844(97)00235-4.
To assess menstrual blood loss and other menstrual characteristics prospectively in women with and without endometriosis.
Three hundred fifteen premenopausal women undergoing laparoscopy for various reasons were asked to complete a pictorial blood loss assessment chart devised by Higham et al to evaluate menstrual flow on which the monthly score has been demonstrated to correlate directly with uterine blood loss measured by the alkaline hematin method. In addition, cycle length and flow duration were recorded. The women also were asked to grade dysmenorrhea severity using a 100-mm visual analogue and a 0-3-points verbal rating scale.
One hundred sixty-three women had endometriosis, and 152 did not. The latter group comprised 59 women with a normal pelvis, 36 with nonendometriotic ovarian cysts, 29 with chronic pelvic inflammatory disease, and 28 with miscellaneous conditions. The median [interquartile range] pictorial blood loss assessment chart score was 110 [66.5-156.5] in women with endometriosis and 84 [56-129] in those without the disease (P = .007); 87 out of 163 (53%) women with endometriosis had a menstrual chart score equal to or greater than 100 compared with 56 out of 152 (37%) of those without (chi 2(1) = 8.02, P = .005; difference = 16%, 95% confidence interval, 6%, 28%). Menstrual flow duration was slightly longer in women with endometriosis (mean difference, 0.33 days). Dysmenorrhea visual analogue and verbal rating scores were significantly higher in the endometriosis than the nonendometriosis group.
According to a visual chart, women with endometriosis had heavier menstrual flow and a significantly higher rate of abnormal menstrual scores that those without the disease.
前瞻性评估患有和未患有子宫内膜异位症的女性的月经失血情况及其他月经特征。
315名因各种原因接受腹腔镜检查的绝经前女性被要求完成一份由海厄姆等人设计的图片式失血评估图表，以评估月经量，该图表的每月评分已被证明与用碱性高铁血红素法测量的子宫失血量直接相关。此外，记录月经周期长度和经期持续时间。这些女性还被要求使用100毫米视觉模拟评分法和0至3分的语言评定量表对痛经严重程度进行分级。
163名女性患有子宫内膜异位症，152名未患。后一组包括59名盆腔正常的女性、36名患有非子宫内膜异位性卵巢囊肿的女性、29名患有慢性盆腔炎的女性和28名患有其他病症的女性。患有子宫内膜异位症的女性的图片式失血评估图表评分中位数[四分位间距]为110[66.5 - 156.5]，未患该病的女性为84[56 - 129](P = .007)；163名患有子宫内膜异位症的女性中有87名(53%)月经图表评分等于或高于100，而未患该病的152名女性中有56名(37%)如此(χ²(1)= 8.02，P = .005；差异 = 16%，95%置信区间，6%，28%)。患有子宫内膜异位症的女性的经期持续时间略长(平均差异为0.33天)。子宫内膜异位症组的痛经视觉模拟评分和语言评定评分显著高于非子宫内膜异位症组。
根据视觉图表，患有子宫内膜异位症的女性月经量比未患该病的女性多，且月经异常评分率显著更高。
