Siwińska A, Głuszek J, Maciejewski J, Musialik D
IInd Clinic of Paediatrics, University School of Medical Science, Poznań, Poland.
Int Urol Nephrol. 1997;29(2):141-6. doi: 10.1007/BF02551333.
This study was designed to assess the effect of i.v. treatment with aminophylline (AMPH) on the risk of calcium phosphate and struvite stone formation. We administered AMPH in doses of 4 mg/kg body weight in 15-min i.v. infusions to 60 infants with clinical symptoms of obstructive bronchitis with dyspnoea. During 3 hours after infusion we observed a significant increase in urine saturation with brushite, octocalcium phosphate and struvite. This rise in urine saturation may increase the risk of kidney stone formation.
本研究旨在评估静脉注射氨茶碱（AMPH）对磷酸钙和鸟粪石结石形成风险的影响。我们以4mg/kg体重的剂量，在15分钟内静脉输注给60名有阻塞性支气管炎伴呼吸困难临床症状的婴儿。在输注后的3小时内，我们观察到透钙磷石、磷酸八钙和鸟粪石的尿液饱和度显著增加。尿液饱和度的这种升高可能会增加肾结石形成的风险。
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