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Synthesis and antiparasitic activities of amidinic azolated derivatives.

作者信息

Danan A, Charon D, Kirkiacharian S, Bories C, Loiseau P M

机构信息

URA 1116 CNRS, Faculté de Pharmacie, Châtenay-Malabry, France.

出版信息

Farmaco. 1997 Apr;52(4):227-9.

PMID:9241827
Abstract

A set of heterocyclic N-acetamidinium hydrochlorides were prepared from the corresponding N-acetonitriles. The antiparasitic screening showed that, while all amidines are practically inactive, some nitriles present leishmanicide properties.

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