极性固定相OV - 225和OV - 275在尿液样本药物检测中的应用。

Application of polar stationary phases OV-225 and OV-275 in the detection of drugs in urine samples.

作者信息

Dadisch G L, Vycudilik W, Machata G

出版信息

Forensic Sci. 1977 Nov-Dec;10(3):205-16. doi: 10.1016/0300-9432(77)90022-x.

Abstract

A procedure for fast screening of urine sample is described. TLC and GC equipped with NPD enable detection of therapeutic doses of drugs to be made in a short time. Tables of retention values for TLC and GC are also presented. TLC detects drugs with a sequence of three reagents. GC screening is carried out with a temperature programmed run of 30 degrees C/min up to 290 degreesC. For the determination of retention indices new polar phases with suitable thermal stabilities such as OV-225 and OV-275 are used.

摘要

本文描述了一种尿液样本快速筛查程序。配备氮磷检测器（NPD）的薄层色谱法（TLC）和气相色谱法（GC）能够在短时间内检测出治疗剂量的药物。文中还给出了TLC和GC的保留值表。TLC通过三种试剂的序列来检测药物。GC筛查采用以30℃/分钟的程序升温运行，直至290℃。为了测定保留指数，使用了具有合适热稳定性的新型极性固定相，如OV - 225和OV - 275。