Gül T, Yilmaztürk A, Erden A C
Department of Gynaekology and Obstetrics, Dicle University, Diyarbakin, Turkey.
Eur J Obstet Gynecol Reprod Biol. 1997 Jul;74(1):37-40. doi: 10.1016/s0301-2115(97)00071-7.
Gestational trophoblastic disease cases encountered in 88 pregnant women during a period between January 1985 and June 1992 were retrospectively studied. During the same period we had 6800 deliveries. The incidence of gestational trophoblastic diseases was 12.9 per 1000 deliveries. Of these cases 72 (81.8%) were diagnosed as hydatidiform mole and 16 (18.2%) were diagnosed as choriocarcinoma in histopathological investigations. The preferred method of treatment for cases of hydatidiform mole was termination with suction curettage and oxytocin perfusion. Trophoblastic diseases were common in women with five or more pregnancies from rural areas and our incidence was higher when compared with similar studies. Moreover, our patients had low socio-economic and poor educational status. All these factors seem to be etiologic reasons, besides multiparity.
对1985年1月至1992年6月期间88例孕妇中遇到的妊娠滋养细胞疾病病例进行了回顾性研究。同期我们有6800例分娩。妊娠滋养细胞疾病的发病率为每1000例分娩中有12.9例。在这些病例中，72例（81.8%）在组织病理学检查中被诊断为葡萄胎，16例（18.2%）被诊断为绒毛膜癌。葡萄胎病例的首选治疗方法是吸刮术加催产素灌注终止妊娠。滋养细胞疾病在来自农村地区且有五次或更多次妊娠的妇女中很常见，与类似研究相比，我们的发病率更高。此外，我们的患者社会经济地位低且教育程度差。除了多产之外，所有这些因素似乎都是病因。
