Bazhanova E D, Grinevich V V, Danilova O A, Chernigovskaia E V
Morfologiia. 1997;111(2):44-6.
Histophysiology of accessory magnocellular nuclei of hypothalamus was studied in young (3-6 months) and old (14-29 months) male Wistar rats. Using non-labeled antibodies to oxytocin and karyolometry activation of protein synthesis combined with inhibition of oxytocin transport along the fibres was shown to occur in 4 (circular, fornical, dorso- and ventrolateral) of 5 accessory nuclei in old rats. This was not observed in anterior commissural nucleus. A hypothesis on compensatory role of accessory magnocellular nuclei of hypothalamus in regulation of neuroendocrine homeostasis in old rats is discussed.
在下丘脑副巨细胞核的组织生理学研究中，选取了年轻（3至6个月）和年老（14至29个月）的雄性Wistar大鼠。通过使用抗催产素的非标记抗体和核仁测量法，结果显示在年老大鼠的5个副核中的4个（环状核、穹窿核、背外侧核和腹外侧核）出现了蛋白质合成激活并伴有沿纤维的催产素运输抑制的情况。在前连合核中未观察到这种现象。文中讨论了关于下丘脑副巨细胞核在年老大鼠神经内分泌稳态调节中的代偿作用的假说。
