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[不同情绪性遗传选择大鼠的催产素能神经分泌系统。形态计量学研究]

[The oxytocinergic neurosecretory system in genetically selected rats differing by their emotionality. Morphometric research].

作者信息

Zhukov D A, Chernigovskaia E V

出版信息

Fiziol Zh Im I M Sechenova. 1994 Apr;80(4):27-31.

PMID:7530083
Abstract

The rats selectively bred for rapid (KHA) and slow (KLA) acquisition of the avoidance response were subjected to inescapable shock (IS). Synthesis and secretion of oxytocin (OT) were higher in intact KLA rats as compared to KHA ones. Preliminary exposure to IS resulted in opposite changes of the OT synthesis and secretion. The findings suggest a dependence of the stress-reactivity of the OT-ergic system on the copying of the behaviour strategy.

摘要

对经选择性培育以快速(KHA)和缓慢(KLA)习得回避反应的大鼠施加不可逃避电击(IS)。与KHA大鼠相比,完整的KLA大鼠中催产素(OT)的合成与分泌更高。初步暴露于IS会导致OT合成与分泌出现相反的变化。这些发现表明OT能系统的应激反应性依赖于行为策略的复制。

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