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[纯失读症:三例病例报告及文献综述]

[Pure alexia: presentation of three cases and review of the literature].

作者信息

García-Hernández I, Gil-Saladié D, Delgado M, Martinell M, Ugarte A, Narberhaus B

机构信息

Servicio de Neurologia, Fundació-Hospital Sant Pere Claver, Barcelona, Espana.

出版信息

Rev Neurol. 1997 Jun;25(142):863-9.

PMID:9244615
Abstract

INTRODUCTION

Pure alexia is a syndrome characterized by the inability to read aloud in the absence of agraphia or apnasia.

CLINICAL CASES

Three clinical cases showing this syndrome are presented. Case I had a left occipital lesion compatible with a subacute haematoma. He had problems with reading, visuo-spatial recognition, digital gnosia and memorizing texts. One year later there was considerable improvement in most of the sub-tests evaluated. There was still deficient colour naming right/left orientation and understanding of letters and words. Case 2 presented with a right homonymous hemianopia and slight left paresis. He had a small left occipital ischaemic infarct. One year later there was improvement on testing, with some deficit still in visual recognition, naming colours and memory. Case 3 presented with right homonymous hemianopia, slight right paresis and a left occipito-parietal expansive lesion. He had defective reading, choosing and naming of colours, right/left orientation and memory. On later evaluation, considerable improvement was seen. There was still colour agnosia, although less severe and mild 'laziness' of the right side.

CONCLUSIONS

In the review of the literature, the disorder and the contributions of various authors, from Déperine in 1892 to the present day, are considered in detail.

摘要

引言

纯失读症是一种综合征,其特征为在无失写症或失用症的情况下无法大声朗读。

临床病例

呈现了三例显示该综合征的临床病例。病例1有一个与亚急性血肿相符的左枕叶病变。他在阅读、视觉空间识别、手指失认和文本记忆方面存在问题。一年后,在评估的大多数子测试中都有了相当大的改善。但在颜色命名、左右定向以及字母和单词理解方面仍存在缺陷。病例2表现为右同向性偏盲和轻度左侧轻瘫。他有一个小的左枕叶缺血性梗死灶。一年后测试有改善,但在视觉识别、颜色命名和记忆方面仍有一些缺陷。病例3表现为右同向性偏盲、轻度右侧轻瘫和一个左枕顶叶占位性病变。他在阅读、颜色选择和命名、左右定向以及记忆方面存在缺陷。在后来的评估中,有了相当大的改善。仍存在颜色失认,尽管没那么严重,右侧还有轻度“迟缓”。

结论

在文献综述中,详细考虑了从1892年的德佩林到当今不同作者对该病症的研究及贡献。

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