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[小剂量免疫球蛋白G治疗不同病因的脱髓鞘性多发性神经病]

[The treatment of demyelinating polyneuropathies of different origins with small doses of immunoglobulin G].

作者信息

Popova L M, Avdiunina I A

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1997;97(5):27-9.

PMID:9245154
Abstract

Application of small doses of IgG-Sandoglobulin (0.16 to 0.98 g per kg of body weight) was quite effective in 2 patients with Guillain-Barré syndrome and in 2 cases of diphtheritic polyneuropathy. These patients had a severe form of the disease with disorders of essential functions. An international course of the disease in one case of IgG treatment was observed. Meanwhile preparation was uneffective in 2 patients with chronic inflammatory demyelinating polyneuropathy caused by lymphoproliferative process. It is worth while to accumulate experience to define optimal doses of the drug.

摘要

小剂量的免疫球蛋白-桑德球蛋白(每公斤体重0.16至0.98克)应用于2例格林-巴利综合征患者和2例白喉性多发性神经病患者时相当有效。这些患者患有严重形式的疾病,伴有基本功能障碍。在1例接受免疫球蛋白治疗的患者中观察到了疾病的整个病程。同时,该制剂对2例由淋巴增殖性病变引起的慢性炎症性脱髓鞘性多发性神经病患者无效。积累经验以确定该药物的最佳剂量是值得的。

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