D'Ari R
Institut Jacques Monod, CNRS, Université Paris 7, Paris, France.
Folia Microbiol (Praha). 1997;42(3):161-4. doi: 10.1007/BF02818972.
The literature demonstrating tight regulation of the Escherichia coli cell cycle is reviewed. Recent evidence is presented indicating that the normal rod cell shape can be abandoned, allowing growth as a coccus, either by increasing the amount of the division proteins FtsZ, FtsA and FtsQ, or by increasing the pool of the nucleotide ppGpp. It is argued that ppGpp may be a cell cycle signal in E. coli.