Pugsley A P, Francetic O, Hardie K, Possot O M, Sauvonnet N, Seydel A
Unité de Génétique Moléculaire, CNRS URA 1149, Institut Pasteur, Paris, France.
Folia Microbiol (Praha). 1997;42(3):184-92. doi: 10.1007/BF02818976.
Pullulanase of Klebsiella oxytoca is one of a wide variety of extracellular proteins that are secreted by Gram-negative bacteria by the complex main terminal branch (MTB) of the general secretory pathway. The roles of some of the 14 components of the MTB are now becoming clear. In this review it is proposed that most of these proteins form a complex, the secretion, that spans the cell envelope to control the opening and closing of channel in the outer membrane. Progress toward the goal of testing this model is reviewed.
产酸克雷伯菌的支链淀粉酶是革兰氏阴性菌通过一般分泌途径的复杂主末端分支（MTB）分泌的多种细胞外蛋白质之一。MTB的14个组分中一些组分的作用现在正逐渐明晰。在这篇综述中，有人提出这些蛋白质中的大多数形成一个复合体，即分泌体，它跨越细胞膜以控制外膜通道的开闭。本文综述了为验证该模型所取得的进展。
