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社区中的强迫症:一项伴有临床重新评估的流行病学调查

Obsessive-compulsive disorder in the community: an epidemiologic survey with clinical reappraisal.

作者信息

Stein M B, Forde D R, Anderson G, Walker J R

机构信息

Department of Psychiatry, University of California, San Diego, La Jolla 92093-0603, USA.

出版信息

Am J Psychiatry. 1997 Aug;154(8):1120-6. doi: 10.1176/ajp.154.8.1120.

DOI:10.1176/ajp.154.8.1120
PMID:9247399
Abstract

OBJECTIVE

To examine the prevalence of obsessive-compulsive symptoms and DSM-IV obsessive-compulsive disorder (OCD), the authors conducted a telephone survey of 2,261 adults in four regions of Canada.

METHOD

Trained lay interviewers administered a modified version of the OCD section of the Comprehensive International Diagnostic Interview. A subsample of respondents with probable cases and probable subclinical cases of OCD was then blindly reinterviewed by research personnel experienced in the assessment of OCD, using the Structured Clinical Interview for DSM-IV and the Yale-Brown Obsessive Compulsive Scale, to confirm the diagnosis and gauge the severity of OCD.

RESULTS

The weighted 1-month prevalence of OCD in the entire sample according to the lay interviews was 3.1%. Upon clinical reappraisal, the 1-month prevalence estimate of OCD dropped to 0.6%; an additional 0.6% had subclinical OCD. The mean Yale-Brown Obsessive Compulsive Scale score of the individuals with OCD was 19.0 (SD = 4.6, median = 21); for those with subclinical OCD, the mean score was 15.4 (SD = 2.4, median = 14). Common reasons for overdiagnosis of OCD by the lay interviewers were inappropriate labeling of worries or concerns as obsessions and overestimating the degree of interference or distress attributable to obsessive-compulsive symptoms.

CONCLUSIONS

OCD, while hardly a rare condition, may be somewhat less prevalent than had been believed on the basis of previous surveys. Additional studies are needed to substantiate these findings and to delineate precisely the extent of disability and reduced quality of life attributable to OCD (and OCD variants) in the community.

摘要

目的

为了调查强迫症状及《精神疾病诊断与统计手册》第四版(DSM-IV)中强迫症(OCD)的患病率,作者对加拿大四个地区的2261名成年人进行了电话调查。

方法

训练有素的非专业访谈员采用了《综合国际诊断访谈》中强迫症部分的修改版。然后,由在强迫症评估方面经验丰富的研究人员,使用《DSM-IV结构临床访谈》和《耶鲁-布朗强迫症量表》,对可能患有强迫症及可能为亚临床强迫症病例的受访者子样本进行盲法再次访谈,以确诊并评估强迫症的严重程度。

结果

根据非专业访谈,整个样本中强迫症的加权1个月患病率为3.1%。经临床重新评估后,强迫症的1个月患病率估计降至0.6%;另有0.6%患有亚临床强迫症。患有强迫症的个体的耶鲁-布朗强迫症量表平均得分为19.0(标准差=4.6,中位数=21);患有亚临床强迫症的个体的平均得分为15.4(标准差=2.4,中位数=14)。非专业访谈员对强迫症过度诊断的常见原因是将担忧或关切不恰当地标记为强迫观念,以及高估强迫症状所致的干扰或痛苦程度。

结论

强迫症虽绝非罕见病症,但可能比之前调查所认为的患病率略低。需要更多研究来证实这些发现,并精确描述社区中因强迫症(及强迫症变体)导致的残疾程度和生活质量下降情况。

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