Piattelli A, Scarano A, Piattelli M, Bertolai R, Panzoni E
Dental School, University of Chieti, Italy.
J Periodontol. 1997 Jul;68(7):694-700. doi: 10.1902/jop.1997.68.7.694.
The authors report the histological features found around three non-submerged titanium plasma-sprayed implants retrieved, after a 10-month loading period, from an autopsy case. At the time of implant insertion, the clinician had noted a wide vestibular dehiscence of the central implant, and it was decided to use a bioabsorbable membrane for guided bone regeneration in this area. After specimen processing, it was possible at low magnification to observe that in the most vestibular slides, the central implant was almost completely surrounded by connective tissue, while in the most lingual slides, the quantity of bone around the implant tended to increase. The other two implants had a bone-implant contact percentage of about 60%. Only in a few areas was mineralized bone in direct contact with the metal surface, while around the major portion of the implant perimeter a layer of unmineralized, red-stained, osteoid material was present. No inflammatory infiltrate was present in the epithelium and in the supracrestal connective tissues. The fibers of this tissue had a different orientation: in the most coronal portion of the implants (smooth surface), they tended to run parallel implant's surface, while in the most apical region (plasma-sprayed surface), they tended to be arranged in a perpendicular fashion. These results, in man, were strikingly similar to those previously reported in dogs and monkeys.
作者报告了从一例尸检病例中取出的3枚非潜入式钛等离子喷涂种植体周围的组织学特征，这些种植体在植入10个月后被取出。在植入种植体时，临床医生注意到中央种植体有较宽的前庭侧骨缺损，因此决定在该区域使用生物可吸收膜进行引导性骨再生。经过标本处理后，在低倍镜下可以观察到，在前庭侧的切片中，中央种植体几乎完全被结缔组织包围，而在舌侧的切片中，种植体周围的骨量有增加的趋势。另外两枚种植体的骨-种植体接触率约为60%。只有在少数区域，矿化骨与金属表面直接接触，而在种植体周边的大部分区域，存在一层未矿化的、红色染色的类骨质材料。上皮组织和龈上结缔组织中均无炎性浸润。该组织的纤维有不同的方向：在种植体最冠方部分（光滑表面），它们倾向于与种植体表面平行排列，而在最根方区域（等离子喷涂表面），它们倾向于垂直排列。在人类身上得到的这些结果与先前在狗和猴子身上报道的结果惊人地相似。
