Gava A, Bertossi L, Zorat P L, Ausili-Cefaro G, Olmi P, Pavanato G, Mandoliti G, Polico C
Istituto di Radioterapia Oncologica, Ospedale di Treviso, Italy.
Rays. 1997 Jan-Mar;22(1 Suppl):61-5.
One hundred ninety-six patients aged > or = 70 years, with non small-cell lung carcinoma and no evidence of metastasis on staging, observed over a 6-month period in 20 Italian Radiotherapy Centers, were analyzed in order to assess indications for treatment, tolerance of radiotherapy (assessed in terms of completion of planned doses and toxicity), and quality of life using the Performance Status and a concise activity of life test. Of the 196 patients studied in 20 Italian Centers, 182 (98%) underwent radiotherapy, 109(60%) of whom with radical intent and 73 (40%) with palliative intent. Of 179 assessable patients undergoing radiation treatment, 163 (91%) completed the treatment as originally planned. Of the 64 assessable patients who completed palliative radiotherapy, relief of symptoms was observed in a percentage ranging from 78% to 86%. Analysis of parameters assessing the quality of life, showed no significant differences in general and functional conditions, as assessed before and upon completion of radiotherapy.
196例年龄≥70岁、患有非小细胞肺癌且分期时无转移证据的患者，于6个月期间在20家意大利放疗中心接受观察，对其进行分析以评估治疗指征、放疗耐受性（根据计划剂量的完成情况和毒性进行评估），并使用体能状态和简明生活活动测试评估生活质量。在20家意大利中心研究的196例患者中，182例（98%）接受了放疗，其中109例（60%）为根治性放疗，73例（40%）为姑息性放疗。在179例可评估的接受放疗的患者中，163例（91%）按原计划完成了治疗。在64例完成姑息性放疗的可评估患者中，症状缓解率在78%至86%之间。对评估生活质量的参数进行分析表明，放疗前和放疗完成后评估的总体和功能状况无显著差异。
