Naik R
Kasturba Medical College, Mangalore.
Indian J Med Sci. 1996 Dec;50(12):339-41.
One hundred fifty histologically non-inflamed appendices from patients with acute appendicular pain were studied for mucosal and submucosal neurogenous hyperplasia using simple histochemical stain. Mucosal and submucosal neural hyperplasia was found in 69.34% of cases. The severity of submucosal hyperplasia was more compared to mucosal. The neural hyperplasia of higher grade was found mainly in the age group between 21 to 40 years. The appendicular pain in three unwarranted surgical cases may be either due to neural hyperplasia or substances liberated from closely associated neuroendocrine/mast cells.
使用简单的组织化学染色法，对150例患有急性阑尾疼痛的患者的组织学上无炎症的阑尾进行了黏膜和黏膜下神经源性增生的研究。69.34%的病例中发现了黏膜和黏膜下神经增生。与黏膜相比，黏膜下增生的严重程度更高。高级别的神经增生主要见于21至40岁的年龄组。3例不必要手术病例中的阑尾疼痛可能是由于神经增生或从紧密相关的神经内分泌/肥大细胞释放的物质所致。
