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75岁以上患者的冠状动脉搭桥手术

[Coronary artery bypass surgery in patients over 75 years].

作者信息

Ura M, Sakata R, Nakayama Y

机构信息

Division of Cardiovascular Surgery, Kumamoto Chuou Hospital, Japan.

出版信息

Kyobu Geka. 1997 Jul;50(8 Suppl):668-72.

PMID:9251491
Abstract

Coronary artery bypass graft surgery is increasingly common in patients over 75 years. In our institution, a consecutive series of 936 patients undergoing isolated CABG between May 1988 and July 1996 included 154 patients older than 75 years. These elderly patients were divided into two group (group A: 40 patients over 80 years old, group B: 114 patients younger than 80 years) and the patients in group A and group B were compared with 100 consecutive patients younger than 75 years who underwent CABG in 1996 (group C). Mean age for elderly patients was 78.1 and for group C patients 64.2 years. Emergency operation and preoperative use of IABP were significantly frequent in group A (p < 0.05). Left main trunk stenosis was more frequent in group A patients (p < 0.05), while the number of diseased vessels did not differ. Mean number of grafts and arterial grafts were higher for group C patients. The frequency of use of arterial grafts in elective cases were lower for group A and group B patients. (p < 0.05, 86.3% group A, 91.3% group B, 100% group C). Although the frequency of mediastinitis and long stay of ICU (over 5 days) were significantly higher in group A (p < 0.05) and older patients tended to have higher postoperative morbidity, the hospital mortality did not differ between the groups (5.0% group A, 4.4% group B, 1.0% group C). We conclude that CABG in patients over 75 years of age can be performed with acceptable mortality. Patients should not be denied CABG because of age alone.

摘要

冠状动脉搭桥手术在75岁以上患者中越来越常见。在我们机构,1988年5月至1996年7月期间连续936例接受单纯冠状动脉搭桥手术的患者中,有154例年龄超过75岁。这些老年患者分为两组(A组:40例年龄超过80岁,B组:114例年龄小于80岁),并将A组和B组患者与1996年连续100例接受冠状动脉搭桥手术的年龄小于75岁的患者(C组)进行比较。老年患者的平均年龄为78.1岁,C组患者为64.2岁。A组急诊手术和术前使用主动脉内球囊反搏(IABP)的情况明显更频繁(p<0.05)。A组患者左主干狭窄更常见(p<0.05),而病变血管数量无差异。C组患者的平均移植血管数量和动脉移植血管数量更高。A组和B组患者在择期病例中使用动脉移植血管的频率较低(p<0.05,A组86.3%,B组91.3%,C组100%)。虽然A组纵隔炎的发生率和重症监护病房(ICU)长时间住院(超过5天)的情况明显更高(p<0.05),老年患者术后发病率往往更高,但各组之间的医院死亡率没有差异(A组5.0%,B组4.4%,C组1.0%)。我们得出结论,75岁以上患者进行冠状动脉搭桥手术可以获得可接受的死亡率。不应仅凭年龄就拒绝患者进行冠状动脉搭桥手术。

相似文献

1
[Coronary artery bypass surgery in patients over 75 years].75岁以上患者的冠状动脉搭桥手术
Kyobu Geka. 1997 Jul;50(8 Suppl):668-72.
2
[Coronary artery bypass surgery in patients aged 75 years and older].75岁及以上患者的冠状动脉搭桥手术
Kyobu Geka. 1997 Jul;50(8 Suppl):660-3.
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Preoperative intraaortic balloon pump enhances cardiac performance and improves the outcome of redo CABG.术前主动脉内球囊反搏可增强心脏功能并改善再次冠状动脉旁路移植术的预后。
Ann Thorac Surg. 1997 Nov;64(5):1237-44. doi: 10.1016/S0003-4975(97)00898-9.
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[Coronary artery bypass surgery in patients over 80 years].
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J Cardiothorac Vasc Anesth. 2005 Oct;19(5):583-8. doi: 10.1053/j.jvca.2005.03.030.
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[Surgical results of coronary artery bypass grafting in patients older than 75 years].75岁以上患者冠状动脉旁路移植术的手术结果
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[Intraaortic balloon pumping in patients undergoing coronary artery bypass grafting].[冠状动脉搭桥手术患者的主动脉内球囊反搏]
Kyobu Geka. 2004 May;57(5):370-3.
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[Coronary bypass surgery in the elderly: characteristics and quality of life].[老年人冠状动脉搭桥手术:特点与生活质量]
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Assessing the risk of waiting for coronary artery bypass graft surgery among patients with stenosis of the left main coronary artery.评估左主干冠状动脉狭窄患者等待冠状动脉搭桥手术的风险。
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引用本文的文献

1
Perioperative features of coronary artery bypass grafting in patients aged 75 years or older.75岁及以上患者冠状动脉旁路移植术的围手术期特征
Jpn J Thorac Cardiovasc Surg. 2002 Apr;50(4):152-7. doi: 10.1007/BF02913196.