Ura M, Sakata R, Nakayama Y
Division of Cardiovascular Surgery, Kumamoto Chuou Hospital, Japan.
Kyobu Geka. 1997 Jul;50(8 Suppl):668-72.
Coronary artery bypass graft surgery is increasingly common in patients over 75 years. In our institution, a consecutive series of 936 patients undergoing isolated CABG between May 1988 and July 1996 included 154 patients older than 75 years. These elderly patients were divided into two group (group A: 40 patients over 80 years old, group B: 114 patients younger than 80 years) and the patients in group A and group B were compared with 100 consecutive patients younger than 75 years who underwent CABG in 1996 (group C). Mean age for elderly patients was 78.1 and for group C patients 64.2 years. Emergency operation and preoperative use of IABP were significantly frequent in group A (p < 0.05). Left main trunk stenosis was more frequent in group A patients (p < 0.05), while the number of diseased vessels did not differ. Mean number of grafts and arterial grafts were higher for group C patients. The frequency of use of arterial grafts in elective cases were lower for group A and group B patients. (p < 0.05, 86.3% group A, 91.3% group B, 100% group C). Although the frequency of mediastinitis and long stay of ICU (over 5 days) were significantly higher in group A (p < 0.05) and older patients tended to have higher postoperative morbidity, the hospital mortality did not differ between the groups (5.0% group A, 4.4% group B, 1.0% group C). We conclude that CABG in patients over 75 years of age can be performed with acceptable mortality. Patients should not be denied CABG because of age alone.
冠状动脉搭桥手术在75岁以上患者中越来越常见。在我们机构,1988年5月至1996年7月期间连续936例接受单纯冠状动脉搭桥手术的患者中,有154例年龄超过75岁。这些老年患者分为两组(A组:40例年龄超过80岁,B组:114例年龄小于80岁),并将A组和B组患者与1996年连续100例接受冠状动脉搭桥手术的年龄小于75岁的患者(C组)进行比较。老年患者的平均年龄为78.1岁,C组患者为64.2岁。A组急诊手术和术前使用主动脉内球囊反搏(IABP)的情况明显更频繁(p<0.05)。A组患者左主干狭窄更常见(p<0.05),而病变血管数量无差异。C组患者的平均移植血管数量和动脉移植血管数量更高。A组和B组患者在择期病例中使用动脉移植血管的频率较低(p<0.05,A组86.3%,B组91.3%,C组100%)。虽然A组纵隔炎的发生率和重症监护病房(ICU)长时间住院(超过5天)的情况明显更高(p<0.05),老年患者术后发病率往往更高,但各组之间的医院死亡率没有差异(A组5.0%,B组4.4%,C组1.0%)。我们得出结论,75岁以上患者进行冠状动脉搭桥手术可以获得可接受的死亡率。不应仅凭年龄就拒绝患者进行冠状动脉搭桥手术。