Wergeland E, Strand K
Department of Preventive Medicine, University of Oslo, Norway.
Int J Gynaecol Obstet. 1997 Aug;58(2):189-96. doi: 10.1016/s0020-7292(97)00083-0.
To study the associations between working conditions and pre-eclampsia.
A cross-sectional study based on questionnaires to all parturients was conducted in Norway from 16 October 1989 to 26 November 1989, with an 87.2% response rate. Of the 5388 responders with singleton pregnancies, 3321 continued in paid work beyond the 3rd month of pregnancy. Pre-eclampsia was recorded if the woman reported hospitalization for hypertension, or if proteinuria and hypertension were diagnosed more than once in the pregnancy.
The prevalence of pre-eclampsia was increased in work involving the lifting of heavy loads of 10-20 kg (adjusted odds ratio (OR), 1.8; 95% CI, 1.2-2.5), hectic work pace (OR, 1.4; 95% CI, 1.0-2.0, P < 0.05), work with hands above shoulder level (OR, 1.4; 95% CI, 1.0-2.2; P = 0.07) and for parous women, shift work (OR, 2.0; 95% CI, 1.1-3.6). It was reduced when the woman had an influence on work pace (OR, 0.7; 95% CI, 0.5-1.0; P = 0.07). Prevalence was also increased with daily consumption of more than four cups of coffee (OR, 1.6; 95% CI, 1.1-2.3).
Prenatal care should include assessment of working conditions, as early improvements may reduce the risk of pre-eclampsia.
研究工作条件与子痫前期之间的关联。
1989年10月16日至1989年11月26日在挪威对所有产妇进行了一项基于问卷调查的横断面研究,应答率为87.2%。在5388名单胎妊娠的应答者中,3321人在怀孕3个月后仍继续从事有薪工作。如果女性报告因高血压住院,或在孕期多次诊断出蛋白尿和高血压,则记录为子痫前期。
在涉及搬运10 - 20千克重物的工作中,子痫前期的患病率增加(校正比值比(OR),1.8;95%置信区间(CI),1.2 - 2.5);工作节奏繁忙(OR,1.4;95% CI,1.0 - 2.0,P < 0.05);工作时双手举过肩部水平(OR,1.4;95% CI,1.0 - 2.2;P = 0.07);对于经产妇,轮班工作(OR,2.0;95% CI,1.1 - 3.6)。当女性能够影响工作节奏时,患病率降低(OR,0.7;95% CI,0.5 - 1.0;P = 0.07)。每天饮用超过四杯咖啡时,患病率也会增加(OR,1.6;95% CI,1.1 - 2.3)。
产前护理应包括对工作条件的评估,因为早期改善可能降低子痫前期的风险。