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Treatment of dystrophic epidermolysis bullosa with autologous meshed split-thickness skin grafts and allogeneic cultured keratinocytes.

作者信息

Verplancke P, Beele H, Monstrey S, Naeyaert J M

机构信息

Department of Dermatology, University Hospital Gent, Belgium.

出版信息

Dermatology. 1997;194(4):380-2. doi: 10.1159/000246155.

DOI:10.1159/000246155
PMID:9252770
Abstract

A 5-year-old boy with dystrophic epidermolysis bullosa (DEB), type generalized mitis, presented with a 2-year-old non-healing skin defect on the presternal and abdominal region. After debridement up to the middle dermis, the defect was grafted with autologous meshed split-thickness grafts from non-involved skin from the thigh and covered with allogeneic keratinocytes. The described method is a valuable therapeutic option in DEB patients who have donor skin areas with a preserved structure of the basement membrane zone.

摘要

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