Gengoux P, Lachapelle J M
Unit of Dermato-Allergology and Dermato-Immunology, Louvain University, Brussels, Belgium.
Dermatology. 1997;194(4):392-4. doi: 10.1159/000246158.
The acquisition of bullous pemphigoid may have different aspects. The disease can be initiated via the development of an excoriated prurigo in which clinical and histological features do not initially suggest the diagnosis of pemphigoid. The presence of eosinophils, oedema or a cleft at the dermis-epidermis junction are not constant features of the histopathological picture. Distinguishing a bullous pemphigoid from a prurigo can only be achieved by direct immunofluorescence.
大疱性类天疱疮的发病可能有不同表现。该病可通过糜烂性痒疹的发展而引发，其临床和组织学特征最初并不提示类天疱疮的诊断。真皮 - 表皮交界处嗜酸性粒细胞、水肿或裂隙的存在并非组织病理学图像的恒定特征。只有通过直接免疫荧光才能将大疱性类天疱疮与痒疹区分开来。
