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促肾上腺皮质激素非依赖性双侧大结节性肾上腺皮质增生导致库欣综合征。

ACTH-independent bilateral macronodular adrenocortical hyperplasia caused Cushing's syndrome.

作者信息

Miyajima A, Nakashima J, Tachibana M, Baba S, Nakamura K, Murai M

机构信息

Department of Urology, Keio University School of Medicine, Tokyo, Japan.

出版信息

Urol Int. 1997;58(4):259-61. doi: 10.1159/000282999.

DOI:10.1159/000282999
PMID:9253133
Abstract

A 53-year-old man who had been followed up for the treatment of hypertension presented with a bilateral adrenal mass during a screening CT scan. Other imaging studies and biochemical tests suggested Cushing's syndrome caused by a pituitary-independent and adrenal-dependent bilateral adrenal tumor. A total adrenalectomy was performed and the pathological appearance of the surgical specimen showed adrenal hyperplasia. Therefore, these findings were considered to be consistent with ACTH-independent bilateral macronodular adrenal hyperplasia (AIMAH). This tumor is quite rare and its etiology still remains controversial. We herein report this incidentally found AIMAH and also review the pertinent literature.

摘要

一名53岁因高血压接受随访治疗的男性,在一次筛查CT扫描中发现双侧肾上腺肿块。其他影像学检查和生化检测提示,该双侧肾上腺肿瘤导致的库欣综合征是由垂体非依赖性和肾上腺依赖性引起的。进行了双侧肾上腺切除术,手术标本的病理表现显示肾上腺增生。因此,这些发现被认为与促肾上腺皮质激素(ACTH)非依赖性双侧大结节性肾上腺增生(AIMAH)相符。这种肿瘤非常罕见,其病因仍存在争议。我们在此报告这例偶然发现的AIMAH,并对相关文献进行综述。

相似文献

1
ACTH-independent bilateral macronodular adrenocortical hyperplasia caused Cushing's syndrome.促肾上腺皮质激素非依赖性双侧大结节性肾上腺皮质增生导致库欣综合征。
Urol Int. 1997;58(4):259-61. doi: 10.1159/000282999.
2
[ACTH-independent bilateral adrenocortical macronodular hyperplasia (AIMAH): report of a case].[促肾上腺皮质激素非依赖性双侧肾上腺皮质大结节性增生(AIMAH):一例报告]
Hinyokika Kiyo. 1995 Jul;41(7):529-32.
3
Non-cushingoid Cushing's syndrome due to adrenocorticotropic hormone-independent bilateral adrenocortical macronodular hyperplasia.促肾上腺皮质激素非依赖性双侧肾上腺皮质大结节性增生所致的非库欣样库欣综合征
Intern Med. 1995 May;34(5):446-50. doi: 10.2169/internalmedicine.34.446.
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A case of Adrenocoricotrophic hormone -independent bilateral adrenocortical macronodular hyperplasia concomitant with primary aldosteronism.一例促肾上腺皮质激素非依赖性双侧肾上腺皮质大结节性增生伴原发性醛固酮增多症。
BMC Surg. 2017 Sep 6;17(1):97. doi: 10.1186/s12893-017-0293-z.
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Aberrant expression of glucagon receptors in adrenal glands of a patient with Cushing's syndrome and ACTH-independent macronodular adrenal hyperplasia.库欣综合征和促肾上腺皮质激素非依赖性大结节性肾上腺增生患者肾上腺中胰高血糖素受体的异常表达。
Medicina (B Aires). 2010;70(3):254-6.
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[Bilateral laparoscopic adrenalectomy in ACTH-independent macronodular adrenal hyperplasia: a case report].[双侧腹腔镜肾上腺切除术治疗促肾上腺皮质激素非依赖性大结节性肾上腺增生:一例报告]
Hinyokika Kiyo. 2002 Jul;48(7):431-4.
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[Cushing's syndrome due to bilateral adrenal macronodular hyperplasia. From ACTH-dependent hypercortisolism to ACTH-independent hypercortisolism].[双侧肾上腺大结节性增生所致库欣综合征。从促肾上腺皮质激素(ACTH)依赖型皮质醇增多症到ACTH非依赖型皮质醇增多症]
Rev Med Chil. 1991 Oct;119(10):1165-70.
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[ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH): a case report].[促肾上腺皮质激素非依赖性双侧大结节性肾上腺皮质增生(AIMAH):一例报告]
Hinyokika Kiyo. 1999 Apr;45(4):245-8.
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A case of severe hypertension caused by ACTH-independent macronodular adrenal hyperplasia.一例由促肾上腺皮质激素非依赖性大结节性肾上腺增生引起的严重高血压病例。
J Endocrinol Invest. 2002 Mar;25(3):254-8. doi: 10.1007/BF03344000.
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Is unilateral adrenalectomy an alternative treatment for ACTH-independent macronodular adrenal hyperplasia?: Long-term follow-up of four cases.单侧肾上腺切除术是促肾上腺皮质激素非依赖性大结节性肾上腺增生的替代治疗方法吗?:4例长期随访
Eur J Endocrinol. 2002 Feb;146(2):237-40. doi: 10.1530/eje.0.1460237.

引用本文的文献

1
A case of severe hypertension caused by ACTH-independent macronodular adrenal hyperplasia.一例由促肾上腺皮质激素非依赖性大结节性肾上腺增生引起的严重高血压病例。
J Endocrinol Invest. 2002 Mar;25(3):254-8. doi: 10.1007/BF03344000.