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利用一些免疫标志物对HIV感染的流行病学过程进行特征描述。

Characterization of the epidemiological process of HIV infection using some immunological markers.

作者信息

Neguţ E A, Usein C R, Mazâlu E, Vrînceanu L, Ionescu G

机构信息

Cantacuzino Institute, Bucharest, Romania.

出版信息

Roum Arch Microbiol Immunol. 1996 Apr-Jun;55(2):89-106.

PMID:9253236
Abstract

In an attempt to elucidate the causes which led to the high percentage of HIV infection in the infantile population in Romania, the paper deals with the study of the evolution of the infection process, in the 0-6 years age group; the process was separately studied in children from closed collectivities (5,318 sera) and children living with their families (2,462). The study of the various patterns obtained with sera analysed by western-blot allowed of concluding that the massive spreading of the infection in both types of infantile population occurred in 1991-1992, the most intense process being reported in the 0-2 years age group (children from closed collectivities). The differences between the evolution of HIV infection epidemic in the above mentioned infantile populations and that noticed in adults are shown.

摘要

为了阐明罗马尼亚婴儿群体中艾滋病毒感染率高的原因,本文探讨了0至6岁年龄组感染过程的演变研究;分别对来自封闭集体的儿童(5318份血清)和与家人生活在一起的儿童(2462份血清)进行了该过程的研究。通过蛋白质印迹法分析血清获得的各种模式的研究表明,两种婴儿群体中的感染大规模传播都发生在1991年至1992年,最严重的过程出现在0至2岁年龄组(来自封闭集体的儿童)。文中展示了上述婴儿群体中艾滋病毒感染流行的演变与成人中观察到的情况之间的差异。

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