Smith L B, Bhattacharya A, Lemasters G, Succop P, Puhala E, Medvedovic M, Joyce J
United States Air Force Armstrong Laboratory, Brooks AFB, Tex, USA.
J Occup Environ Med. 1997 Jul;39(7):623-32. doi: 10.1097/00043764-199707000-00007.
This study used the postural stability technique to investigate the neurological effects of cumulative low-level exposure to raw JP-8 jet fuel vapor on aircraft maintenance personnel. All subjects performed two sets of four 30-second postural sway tests. The results of mean cumulative exposure levels (in parts per million +/- standard error of mean) were the following: naphthas, 1308 +/- 292; benzene, 21.2 +/- 5.7; toluene, 23.8 +/- 6.1; and m-,o-, p-xylene, 22.7 +/- 5.4. Covariate adjusted regression analysis of the exposed group data showed a statistically significant association (P < 0.05) between the solvents (benzene, toluene, and xylene) and increased postural sway response. For all solvent exposures, the "eyes closed, on foam" test provided the strongest association between sway length and JP-8 benzene (r2 range, 0.45 to 0.52), implying subtle influence on vestibular/proprioception functionalities.
本研究采用姿势稳定性技术，调查飞机维修人员长期低水平接触未加工的JP-8喷气燃料蒸汽的神经学影响。所有受试者进行了两组，每组四次，每次30秒的姿势摇摆测试。平均累积暴露水平（百万分率±平均标准误差）结果如下：石脑油，1308±292；苯，21.2±5.7；甲苯，23.8±6.1；间二甲苯、邻二甲苯、对二甲苯，22.7±5.4。对暴露组数据进行协变量调整回归分析显示，溶剂（苯、甲苯和二甲苯）与姿势摇摆反应增加之间存在统计学显著关联（P<0.05）。对于所有溶剂暴露情况，“闭眼，站在泡沫上”测试显示摇摆长度与JP-8苯之间的关联最强（r2范围为0.45至0.52），这意味着对前庭/本体感觉功能有微妙影响。
