Rahman W A
School of Biological Sciences, Universiti Sains Malaysia, Minden, Penang.
Southeast Asian J Trop Med Public Health. 1996 Dec;27(4):765-7.
Trials using albendazole and mebendazole, as single 400 mg dose treatments, against soil-transmitted helminths, were carried out in 7-9 and 10-12 years-old schoolchildren living in urban and rural environments in Penang, Malaysia. Both drugs were equally effective in treating trichuriasis and ascariasis in both age groups and environments. However, mebendazole is not so effective in the treatment for hookworms when compared to albendazole. It is suggested that albendazole should be considered the drug of choice for mass chemotherapy for Penang.
在马来西亚槟城，针对生活在城乡环境中的7至9岁和10至12岁学童，开展了使用阿苯达唑和甲苯达唑单次400毫克剂量治疗土壤传播蠕虫的试验。在两个年龄组和两种环境中，这两种药物在治疗鞭虫病和蛔虫病方面同样有效。然而，与阿苯达唑相比，甲苯达唑在治疗钩虫病方面效果欠佳。建议将阿苯达唑视为槟城大规模化疗的首选药物。
