服用甲氧苄啶后出现双侧前葡萄膜炎和视网膜出血。

Bilateral anterior uveitis and retinal haemorrhages after administration of trimethoprim.

作者信息

Kristinsson J K, Hannesson O B, Sveinsson O, Thorleifsson H

机构信息

Department of Ophthalmology, University of Iceland, Landakotsspítali, Reykjavík.

出版信息

Acta Ophthalmol Scand. 1997 Jun;75(3):314-5. doi: 10.1111/j.1600-0420.1997.tb00783.x.

DOI:10.1111/j.1600-0420.1997.tb00783.x

PMID:9253984

Abstract

In this case report we present a female patient with recurrent urinary infection treated with trimethoprim/sulfamethoxazole, trimethoprim alone and ciprofloxacin. She developed adverse systemic symptoms and bilateral anterior uveitis following administration of the former two drugs, and in addition retinal haemorrhages after the use of trimethoprim. Uveitis and retinal haemorrhages are rare side effects of trimethoprim/sulfamethoxazole. To our best knowledge they have not been described as a side effect of trimethoprim alone.

摘要

在本病例报告中，我们呈现了一名患有复发性尿路感染的女性患者，她先后接受了甲氧苄啶/磺胺甲恶唑、单用甲氧苄啶和环丙沙星治疗。在使用前两种药物后，她出现了全身性不良反应和双侧前葡萄膜炎，此外，在使用甲氧苄啶后还出现了视网膜出血。葡萄膜炎和视网膜出血是甲氧苄啶/磺胺甲恶唑罕见的副作用。据我们所知，它们尚未被描述为单用甲氧苄啶的副作用。