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Alterations of Na+ channel gating in myotonia.

作者信息

Ruff R L

机构信息

Department of Neurology, Cleveland Veterans Administration Medical center, Case Western Reserve University Medical School, Cleveland, OH, USA

出版信息

J Physiol. 1997 Mar 15;499 ( Pt 3)(Pt 3):571. doi: 10.1113/jphysiol.1997.sp021950.

DOI:10.1113/jphysiol.1997.sp021950
PMID:9254302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1159276/
Abstract
摘要

相似文献

1
Alterations of Na+ channel gating in myotonia.肌强直中钠离子通道门控的改变。
J Physiol. 1997 Mar 15;499 ( Pt 3)(Pt 3):571. doi: 10.1113/jphysiol.1997.sp021950.
2
Human sodium channel gating defects caused by missense mutations in S6 segments associated with myotonia: S804F and V1293I.与肌强直相关的S6片段错义突变导致的人类钠通道门控缺陷:S804F和V1293I。
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Spectrum of sodium channel disturbances in the nondystrophic myotonias and periodic paralyses.非营养不良性肌强直和周期性瘫痪中钠通道紊乱的谱系
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Different effects on gating of three myotonia-causing mutations in the inactivation gate of the human muscle sodium channel.人类肌肉钠通道失活门中三种致强直突变对门控的不同影响。
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A C-terminal skeletal muscle sodium channel mutation associated with myotonia disrupts fast inactivation.一种与肌强直相关的C末端骨骼肌钠通道突变会破坏快速失活。
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本文引用的文献

1
Human Na+ channel fast and slow inactivation in paramyotonia congenita mutants expressed in Xenopus laevis oocytes.非洲爪蟾卵母细胞中表达的先天性副肌强直突变体中的人类钠离子通道快速和慢速失活
J Physiol. 1997 Mar 15;499 ( Pt 3)(Pt 3):589-600. doi: 10.1113/jphysiol.1997.sp021952.
2
Single-channel basis of slow inactivation of Na+ channels in rat skeletal muscle.大鼠骨骼肌中钠通道缓慢失活的单通道基础
Am J Physiol. 1996 Sep;271(3 Pt 1):C971-81. doi: 10.1152/ajpcell.1996.271.3.C971.
3
Impaired slow inactivation in mutant sodium channels.突变钠通道中缓慢失活受损。
Biophys J. 1996 Jul;71(1):227-36. doi: 10.1016/S0006-3495(96)79219-6.
4
Slow inactivation of sodium channels: more than just a laboratory curiosity.钠通道的缓慢失活:不仅仅是实验室里的新奇现象。
Biophys J. 1996 Jul;71(1):5-7. doi: 10.1016/S0006-3495(96)79203-2.
5
Ion-channel defects and aberrant excitability in myotonia and periodic paralysis.肌强直和周期性瘫痪中的离子通道缺陷与异常兴奋性。
Trends Neurosci. 1996 Jan;19(1):3-10. doi: 10.1016/0166-2236(96)81859-5.
6
Slow Na+ channel inactivation must be disrupted to evoke prolonged depolarization-induced paralysis.必须破坏缓慢的钠离子通道失活,以诱发延长的去极化诱导麻痹。
Biophys J. 1994 Feb;66(2 Pt 1):542. doi: 10.1016/s0006-3495(94)80807-0.