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Slow inactivation of sodium channels: more than just a laboratory curiosity.

作者信息

Cannon S C

机构信息

Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02114, USA.

出版信息

Biophys J. 1996 Jul;71(1):5-7. doi: 10.1016/S0006-3495(96)79203-2.

DOI:10.1016/S0006-3495(96)79203-2
PMID:8804584
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1233452/
Abstract
摘要

相似文献

1
Slow inactivation of sodium channels: more than just a laboratory curiosity.钠通道的缓慢失活：不仅仅是实验室里的新奇现象。
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2
Impaired slow inactivation in mutant sodium channels.突变钠通道中缓慢失活受损。
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3
Periodic paralyses: when channels go wrong.
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4
Hyperkalemic periodic paralysis with cardiac dysrhythmia: a novel sodium channel mutation?伴有心律失常的高钾性周期性麻痹：一种新型钠通道突变？
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Activation and inactivation of the voltage-gated sodium channel: role of segment S5 revealed by a novel hyperkalaemic periodic paralysis mutation.电压门控钠通道的激活与失活：一种新型高钾性周期性麻痹突变揭示的S5片段的作用
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Bridging the gap between anomalous sodium channel molecules and aberrant physiology.弥合异常钠通道分子与异常生理学之间的差距。
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7
Spectrum of sodium channel disturbances in the nondystrophic myotonias and periodic paralyses.非营养不良性肌强直和周期性瘫痪中钠通道紊乱的谱系
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Single-channel analysis of inactivation-defective rat skeletal muscle sodium channels containing the F1304Q mutation.对含有F1304Q突变的失活缺陷型大鼠骨骼肌钠通道进行单通道分析。
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A double mutation in families with periodic paralysis defines new aspects of sodium channel slow inactivation.周期性麻痹家族中的双突变揭示了钠通道缓慢失活的新情况。
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Slow inactivation differs among mutant Na channels associated with myotonia and periodic paralysis.与肌强直和周期性麻痹相关的突变钠通道之间的缓慢失活存在差异。
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引用本文的文献

1
Slow inactivation of the NaV1.4 sodium channel in mammalian cells is impeded by co-expression of the beta1 subunit.在哺乳动物细胞中，β1亚基的共表达会阻碍NaV1.4钠通道的缓慢失活。
Pflugers Arch. 2009 Apr;457(6):1253-63. doi: 10.1007/s00424-008-0600-8. Epub 2008 Oct 22.
2
Slow inactivation does not block the aqueous accessibility to the outer pore of voltage-gated Na channels.缓慢失活并不阻碍电压门控钠通道外孔的水相可及性。
J Gen Physiol. 2002 Oct;120(4):509-16. doi: 10.1085/jgp.20028672.
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Slow removal of Na(+) channel inactivation underlies the temporal filtering property in the teleost thalamic neurons.硬骨鱼丘脑神经元的时间滤波特性的基础是钠离子通道失活的缓慢解除。
J Physiol. 2002 Mar 15;539(Pt 3):743-53. doi: 10.1113/jphysiol.2001.013061.
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A structural rearrangement in the sodium channel pore linked to slow inactivation and use dependence.钠通道孔中的一种结构重排与缓慢失活和使用依赖性相关。
J Gen Physiol. 2000 Nov;116(5):653-62. doi: 10.1085/jgp.116.5.653.
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Enhanced slow inactivation by V445M: a sodium channel mutation associated with myotonia.V445M增强慢失活：一种与肌强直相关的钠通道突变
Biophys J. 1999 Feb;76(2):861-8. doi: 10.1016/S0006-3495(99)77249-8.
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Inactivation of single cardiac Na+ channels in three different gating modes.三种不同门控模式下单一心脏钠通道的失活
Biophys J. 1998 Oct;75(4):1740-8. doi: 10.1016/S0006-3495(98)77615-5.
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Slow inactivation does not affect movement of the fast inactivation gate in voltage-gated Na+ channels.缓慢失活并不影响电压门控钠通道中快速失活门的移动。
J Gen Physiol. 1998 Jan;111(1):83-93. doi: 10.1085/jgp.111.1.83.
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Slow recovery from inactivation of Na+ channels underlies the activity-dependent attenuation of dendritic action potentials in hippocampal CA1 pyramidal neurons.钠通道失活后的缓慢恢复是海马体CA1锥体神经元中树突动作电位的活动依赖性衰减的基础。
J Neurosci. 1997 Sep 1;17(17):6512-21. doi: 10.1523/JNEUROSCI.17-17-06512.1997.
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Alterations of Na+ channel gating in myotonia.肌强直中钠离子通道门控的改变。
J Physiol. 1997 Mar 15;499 ( Pt 3)(Pt 3):571. doi: 10.1113/jphysiol.1997.sp021950.
10
Effect of alkali metal cations on slow inactivation of cardiac Na+ channels.碱金属阳离子对心脏钠通道缓慢失活的影响。
J Gen Physiol. 1997 Jul;110(1):23-33. doi: 10.1085/jgp.110.1.23.

本文引用的文献

1
Impaired slow inactivation in mutant sodium channels.突变钠通道中缓慢失活受损。
Biophys J. 1996 Jul;71(1):227-36. doi: 10.1016/S0006-3495(96)79219-6.
2
Ion-channel defects and aberrant excitability in myotonia and periodic paralysis.肌强直和周期性瘫痪中的离子通道缺陷与异常兴奋性。
Trends Neurosci. 1996 Jan;19(1):3-10. doi: 10.1016/0166-2236(96)81859-5.
3
Slow Na+ channel inactivation must be disrupted to evoke prolonged depolarization-induced paralysis.必须破坏缓慢的钠离子通道失活，以诱发延长的去极化诱导麻痹。
Biophys J. 1994 Feb;66(2 Pt 1):542. doi: 10.1016/s0006-3495(94)80807-0.
4
Voltage clamp of rat and human skeletal muscle: measurements with an improved loose-patch technique.大鼠和人类骨骼肌的电压钳制：采用改良的膜片松散钳技术进行测量。
J Physiol. 1984 Feb;347:751-68. doi: 10.1113/jphysiol.1984.sp015094.
5
Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.鱿鱼巨大轴突中钠电导的缓慢失活。对链霉蛋白酶的抗性。
J Physiol. 1978 Oct;283:1-21. doi: 10.1113/jphysiol.1978.sp012485.