[支气管哮喘患者支气管高反应性机制中钙稳态与脂质过氧化的耦合]
[Coupling of calcium homeostasis and lipid peroxidation in mechanisms of bronchial hyperreactivity in patients with bronchial asthma].
作者信息
Amatuni V G, Malaian K L
出版信息
Vopr Med Khim. 1996 Oct-Dec;42(4):314-8.
PMID:9254518
Abstract
A comparative study of calcium homeostasis, calcium regulating system and lipid peroxidation has been done with 16 bronchial asthma patients (BA) at bronchospasm of physical effort (BPhE) and with 15 asthma attack patients in remission period. The data obtained point to the close pathogenetic link between the changes of calcium homeostasis, hormonal calcium regulating system and LPO strengthening the appearance of hyperreactivity of bronchial tree and BA.
摘要
对16例处于体力负荷诱发支气管痉挛（BPhE）状态的支气管哮喘患者（BA）和15例处于缓解期的哮喘发作患者进行了钙稳态、钙调节系统及脂质过氧化的对比研究。所获数据表明，钙稳态变化、激素钙调节系统及脂质过氧化增强之间存在密切的发病机制联系，这强化了支气管树高反应性及支气管哮喘的出现。
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