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南非不完全流产的流行病学。国家不完全流产参考小组。

The epidemiology of incomplete abortion in South Africa. National Incomplete Abortion Reference Group.

作者信息

Rees H, Katzenellenbogen J, Shabodien R, Jewkes R, Fawcus S, McIntyre J, Lombard C, Truter H

机构信息

Department of Obstetrics and Gynaecology, University of the Witwatersrand, Johannesburg.

出版信息

S Afr Med J. 1997 Apr;87(4):432-7.

PMID:9254785
Abstract

OBJECTIVE

To describe the epidemiology of incomplete abortion (spontaneous miscarriage and illegally induced) in South Africa.

DESIGN

Multicentre, prospective, descriptive study.

SETTING

Fifty-six public hospitals in nine provinces (a stratified, random sample of all hospitals treating gynaecological emergencies).

PATIENTS

All women of gestation under 22 weeks who presented with incomplete abortion during the 2-week study period.

MAIN OUTCOME MEASURES

Incidence of, morbidity associated with and mortality from incomplete abortion.

MAIN RESULTS

An estimated 44686 (95% CI 35633-53709) women per year were admitted to South Africa's public hospitals with incomplete abortion. An estimated 425 (95% CI 78-735) women die in public hospitals from complications of abortion. Fifteen per cent (95% CI 13-18) of patients have severe morbidity while a further 19% (95% CI 16-22) have moderate morbidity, as assessed by categories designed for the study which largely reflect infection. There were marked inter-provincial differences and inter-age group differences in trimester of presentation and proportion of patients with appreciable morbidity.

CONCLUSIONS

Incomplete abortions and, in particular, unsafe abortions are an important cause of mortality and morbidity in South Africa. The methods used in this study underestimate the true incidence for reasons that are discussed. A high priority should be given to the prevention of unsafe abortion.

摘要

目的

描述南非不完全流产(自然流产和非法人工流产)的流行病学情况。

设计

多中心、前瞻性、描述性研究。

地点

九个省份的56家公立医院(从所有治疗妇科急症的医院中分层随机抽样)。

患者

在为期2周的研究期间出现不完全流产的所有妊娠22周以下的女性。

主要观察指标

不完全流产的发病率、相关发病率及死亡率。

主要结果

估计每年有44686名(95%可信区间35633 - 53709)女性因不完全流产入住南非公立医院。估计有425名(95%可信区间78 - 735)女性在公立医院死于流产并发症。根据为本研究设计的、主要反映感染情况的分类评估,15%(95%可信区间13 - 18)的患者有严重发病情况,另有19%(95%可信区间16 - 22)有中度发病情况。在孕周分布以及有明显发病情况的患者比例方面,省与省之间和年龄组之间存在显著差异。

结论

不完全流产,尤其是不安全流产,是南非死亡和发病的重要原因。本研究采用的方法因文中讨论的原因低估了真实发病率。应高度重视预防不安全流产。

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