Cohen P T
Department of Biochemistry, University of Dundee, Scotland, UK.
Trends Biochem Sci. 1997 Jul;22(7):245-51. doi: 10.1016/s0968-0004(97)01060-8.
The dephosphorylation of proteins on serine and threonine residues is a major mechanism of cellular regulation. Many novel protein serine/threonine phosphatases in the PPP family have recently been discovered and the insights that have been gained into their different functions are summarised in this review.
蛋白质丝氨酸和苏氨酸残基的去磷酸化是细胞调节的主要机制。最近在PPP家族中发现了许多新型蛋白质丝氨酸/苏氨酸磷酸酶,本综述总结了对其不同功能的见解。