Blomqvist P, Ekbom A, Carlsson P, Ahlstrand C, Johansson J E
Department of Cancer Epidemiology, University Hospital, Uppsala, Sweden.
Urology. 1997 Aug;50(2):214-9; discussion 219-20. doi: 10.1016/S0090-4295(97)00241-0.
To assess health care use and costs for benign prostatic hyperplasia (BPH) in Sweden from 1987 to 1994 when minimal invasive procedures, including transurethral microwave therapy (TUMT) and drugs, were introduced, in addition to conventional surgery.
Cross-sectional annual data on health care utilization based on national information systems and surveys were used for calculation of direct 1994 cost.
The total number of men in the age group at risk for BPH was virtually constant, and the total direct health care costs for BPH treatment increased from 1987 to 1992. A slight decrease was evident for the years 1993 and 1994, notwithstanding the introduction of new ambulatory procedures in 1991 and of new drugs in 1992. The number of physician office visits changed little during the study period, although this estimate may be low. TUMT procedures were introduced rapidly but decreased; nevertheless, their share was never more than 3% of total costs. Drug sales were 15-fold those in 1992 and accounted for 12% of the total costs in 1994. Conventional transurethral resection of the prostate (TURP) operations decreased markedly after the introduction of the new treatments.
The new treatments were adopted differently. TUMT procedures decreased as rapidly as they were introduced. Three years after the introduction of the new drugs, drug sales indicated that the number of men receiving drug treatment was greater than the annual number of men receiving TURP operations and TUMT procedures combined. Yet the total costs showed a slight decrease, mainly due to the decreasing numbers of TURP operations.
评估1987年至1994年瑞典良性前列腺增生(BPH)的医疗保健使用情况及费用,此期间除了传统手术外,还引入了包括经尿道微波热疗(TUMT)和药物在内的微创治疗方法。
基于国家信息系统和调查得出的关于医疗保健利用情况的年度横断面数据,用于计算1994年的直接费用。
BPH风险年龄组男性总数基本保持不变,1987年至1992年BPH治疗的直接医疗总费用有所增加。尽管1991年引入了新的门诊手术,1992年引入了新药,但1993年和1994年仍有轻微下降。研究期间,医师门诊次数变化不大,不过这一估计可能偏低。TUMT手术迅速引入但随后减少;然而,其费用占比从未超过总费用的3%。1994年药品销售额是1992年的15倍,占总费用的12%。新治疗方法引入后,传统经尿道前列腺切除术(TURP)手术显著减少。
新治疗方法采用情况各异。TUMT手术引入和减少的速度一样快。新药引入三年后,药品销售额表明接受药物治疗的男性人数多于每年接受TURP手术和TUMT手术的男性人数总和。然而,总费用略有下降,主要是由于TURP手术数量减少。