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良性前列腺增生患者的治疗模式与护理成本研究

An examination of treatment patterns and costs of care among patients with benign prostatic hyperplasia.

作者信息

Black Libby, Naslund Michael James, Gilbert Thomas D, Davis E Anne, Ollendorf Daniel A

机构信息

PharMetrics, Inc., 311 Arsenal Street, Watertown, MA 02472, USA.

出版信息

Am J Manag Care. 2006 Mar;12(4 Suppl):S99-S110.

Abstract

OBJECTIVE

To examine utilization and costs of care for benign prostatic hyperplasia (BPH)-related services in a large cohort of commercially insured persons.

METHODS

Pharmacy and medical claims data were obtained from 61 US healthcare plans. Men aged > or = 45 years who were newly diagnosed with BPH between January 2000 and March 2001 were identified. Each patient was followed for 12 months after diagnosis; utilization and costs were calculated for common procedures and disease-related events. Costs were estimated based on health plan payments. Univariate statistics were provided for relevant measures.

RESULTS

A total of 77 040 patients were selected (mean age, 58.1 years). Thirty-six percent of patients had 1 or more urologist visits in the year after diagnosis. Two thirds of patients had a prostate-specific antigen test, whereas 7% had a prostate biopsy. A total of 14 392 patients (18.7%) received an alpha blocker during follow-up; 1860 patients (2.4%) received a 5-alpha reductase inhibitor. Approximately 2% of patients had a surgical procedure (either invasive or minimally invasive); transurethral prostatectomy costs averaged approximately dollar 5600, consisting of mean (standard deviation) costs of dollar 794 (dollar 470) for the procedure and dollar 4810 (dollar 8487) in associated inpatient costs. Re-treatment was common (18.7%) among patients with a surgical procedure, at a mean cost of dollar 1888 (dollar 1636).

CONCLUSION

Most patients newly diagnosed with BPH appear to undergo watchful waiting in the year after diagnosis. Although rates of surgical intervention and adverse events at 1 year are low, these events are costly. Strategies to prevent or delay the need for surgery, such as regular examinations, testing, and use of pharmacotherapy where indicated, may further reduce the need for surgical intervention.

摘要

目的

在一大群商业保险人群中,研究与良性前列腺增生(BPH)相关服务的使用情况及护理成本。

方法

从61家美国医疗保健计划中获取药房和医疗理赔数据。确定2000年1月至2001年3月期间新诊断为BPH的年龄≥45岁的男性。每位患者在诊断后随访12个月;计算常见手术和疾病相关事件的使用情况及成本。成本根据医疗保健计划支付情况估算。提供相关指标的单变量统计数据。

结果

共选择了77040名患者(平均年龄58.1岁)。36%的患者在诊断后的一年内有1次或更多次泌尿外科就诊。三分之二的患者进行了前列腺特异性抗原检测,而7%的患者进行了前列腺活检。共有14392名患者(18.7%)在随访期间接受了α受体阻滞剂治疗;1860名患者(2.4%)接受了5α还原酶抑制剂治疗。约2%的患者接受了手术治疗(无论是侵入性还是微创性);经尿道前列腺切除术的平均成本约为5600美元,包括该手术的平均(标准差)成本794美元(470美元)和相关住院成本4810美元(8487美元)。手术患者再次治疗很常见(18.7%),平均成本为1888美元(1636美元)。

结论

大多数新诊断为BPH的患者在诊断后的一年内似乎采取观察等待策略。尽管1年内手术干预率和不良事件发生率较低,但这些事件成本高昂。预防或延迟手术需求的策略,如定期检查、检测以及在有指征时使用药物治疗,可能会进一步减少手术干预的需求。

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