Caumes E, Bricaire F
Service de Maladies Infectieuses et Tropicales, GH Pitié-Salpêtrière, Paris.
Ann Med Interne (Paris). 1997;148(3):255-7.
Reactivation of Herpes simplex virus and varicella zoster virus infections occurs frequently in patients infected with human immunodeficiency virus (HIV). Prevention of Herpes simplex recurrences with oral acyclovir (400 mg x 2/day) should be recommended for patients with more than 6 relapses per year. Varicella-zoster immunoglobulin is recommended for prophylaxis of varicella in exposed HIV-infected adults and children who are susceptible. Prevention of varicella-zoster recurrences with oral acyclovir (800 mg x 5/day) should be considered for patients with retinopathy.
单纯疱疹病毒和水痘带状疱疹病毒感染在感染人类免疫缺陷病毒(HIV)的患者中频繁复发。对于每年复发超过6次的患者,建议口服阿昔洛韦(400毫克×2/天)预防单纯疱疹复发。对于暴露后易感染的HIV感染成人和儿童,建议使用水痘带状疱疹免疫球蛋白预防水痘。对于患有视网膜病变的患者,应考虑口服阿昔洛韦(800毫克×5/天)预防水痘带状疱疹复发。