McIndoe A K, Stewart P, Wilson I H
Department of Anaesthesia & Intensive Care, Royal Devon & Exeter Hospital (Wonford), U.K.
Intensive Care Med. 1997 Jun;23(6):704-7. doi: 10.1007/s001340050398.
We have undertaken a laboratory study to determine whether a drawover vaporizer in the inspiratory limb of an intensive care ventilator circuit can produce safe and therapeutic concentrations of isoflurane.
An Oxford Miniature Vaporizer (OMV) and Ohmeda TEC vaporizer were assessed over the range of inspired isoflurane concentrations, airway pressures and tidal volumes experienced in the ICU.
The experimental findings suggest that the OMV inhaler in plenum mode can be relied upon to produce safe concentrations of isoflurane over a clinically useful range of inspired concentrations. Furthermore, it behaves predictably over the range of airway pressures likely to be encountered in the patient admitted with acute severe asthma. However, we found that the Ohmeda TEC vaporizer did not perform reliably in this setting.
我们进行了一项实验室研究，以确定重症监护呼吸机回路吸气支路上的 Drawover 蒸发器能否产生安全且具有治疗作用的异氟烷浓度。
在重症监护病房（ICU）所经历的吸入异氟烷浓度、气道压力和潮气量范围内，对牛津微型蒸发器（OMV）和 Ohmeda TEC 蒸发器进行了评估。
实验结果表明，处于增压模式的 OMV 吸入器在临床上有用的吸入浓度范围内能够可靠地产生安全的异氟烷浓度。此外，在急性重症哮喘患者可能遇到的气道压力范围内，其表现具有可预测性。然而，我们发现 Ohmeda TEC 蒸发器在这种情况下表现不可靠。
