Furuya S, Ogura H, Tanaka Y, Tsukamoto T, Daikuzono N, Liong M L
Urological Service, Furuya Hospital, Kitami, Japan.
Int J Urol. 1997 May;4(3):265-8. doi: 10.1111/j.1442-2042.1997.tb00186.x.
Twelve patients with benign prostatic hyperplasia and urinary retention, who were considered to be poor candidates for prostatectomy, were treated by transurethral balloon laser thermotherapy (TUBAL-T). The mean patient age was 78.9 years (range, 66 to 93 years) and the mean duration of bladder catheterization was 11 weeks (range, 2 to 48 weeks).
Irradiation into the prostatic tissue was done through 360 degrees with a neodymium: yttrium aluminum garnet (Nd:YAG) laser balloon placed in the prostatic urethra, with pain relief provided by using local topical anesthesia. The total laser dose was from 45,000 to 123,376 J, with an average of 73,089 J. The irradiation time was from 40 to 54 minutes, with an average of 45.2 minutes.
Spontaneous voiding became possible in all patients at a mean of 2.8 days (range, 1 to 7 days) after irradiation. The mean catheter-free period was 20.5 months (range, 6 to 34 months), with the longest being 34 months. The international prostatic symptom scores, quality-of-life scores, and peak uroflow rates showed substantial improvement after laser thermotherapy. To date, long-term resumption of spontaneous voiding was successfully achieved in 9 of 12 cases (75%).
TUBAL-T is safe and effective alternative for treatment of urinary retention in patients with benign prostatic hyperplasia who are considered to be at high surgical risk.
12例良性前列腺增生伴尿潴留患者被认为不适合进行前列腺切除术，接受了经尿道球囊激光热疗（TUBAL-T）。患者平均年龄为78.9岁（范围66至93岁），膀胱导尿平均持续时间为11周（范围2至48周）。
将钕：钇铝石榴石（Nd：YAG）激光球囊置于前列腺尿道，360度照射前列腺组织，使用局部表面麻醉缓解疼痛。总激光剂量为45,000至123,376焦耳，平均为73,089焦耳。照射时间为40至54分钟，平均为45.2分钟。
所有患者在照射后平均2.8天（范围1至7天）可自行排尿。平均无导尿期为20.5个月（范围6至34个月），最长为34个月。国际前列腺症状评分、生活质量评分和最大尿流率在激光热疗后均有显著改善。迄今为止，12例中有9例（75%）成功实现了长期自行排尿。
对于被认为手术风险高的良性前列腺增生伴尿潴留患者，TUBAL-T是一种安全有效的治疗方法。
