Goodyear B G, Gati J S, Menon R S
Department of Medical Biophysics, University of Western Ontario, Canada.
Magn Reson Med. 1997 Aug;38(2):183-6. doi: 10.1002/mrm.1910380204.
A rapid method of generating functional scout images to map cortical activity is presented. Maps were produced immediately "on-line" on the scanner's console using fast low-angle shot gradient-recalled echo and echo-planar imaging sequences without special hardware. To demonstrate the technique, raw data collected during photic stimulation and dark control periods were subtracted through phase alternation of the receiver with constant transmitted radio frequency phase. A blood oxygen level-dependent signal difference map was produced by magnitude reconstruction of the resulting complex-difference data. Maps improved in contrast with an increasing number of stimulation-control cycles and showed similar areas of activation to traditional fMRI processing methods. Such a functional scout procedure allows rapid localization of brain function within the anatomical region of interest. From these functional scout images, slices or voxels may be planned by using the scanner manufacturers prescription tools for further specialized studies.
本文介绍了一种快速生成功能性侦察图像以绘制皮质活动图谱的方法。使用快速低角度激发梯度回波和回波平面成像序列，无需特殊硬件，即可在扫描仪控制台上立即“在线”生成图谱。为了演示该技术，通过在恒定发射射频相位下使接收器进行相位交替，对光刺激和暗对照期间收集的原始数据进行相减。通过对所得复数差数据进行幅度重建，生成了血氧水平依赖信号差异图。随着刺激 - 对照周期数的增加，图谱的对比度得到改善，并且显示出与传统功能磁共振成像处理方法相似的激活区域。这种功能性侦察程序能够在感兴趣的解剖区域内快速定位脑功能。根据这些功能性侦察图像，可以使用扫描仪制造商的处方工具规划切片或体素，以进行进一步的专门研究。
