Senanayake M P, Perera A S, De Silva T U
University of Colombo.
Ceylon Med J. 1997 Jun;42(2):69-71.
To study the integrity of EPI vaccine storage during interruptions to the power supply.
Health centres in Colombo District.
An interviewer-administered questionnaire was used to collect information on staff compliance with regulations of the expanded program of immunisation (EPI) and alternative facilities available for refrigeration during power failure. The refrigerator and storage conditions were inspected. The stored vaccines were tagged with thermosensitive cold chain monitors, which were read on revisiting the clinic 14 days later. During the study period, power cuts of 2 hours' duration were in force daily. A control study was carried out when there was no interruption to power supply.
Diphtheria-pertussis-tetanus (DPT) and measles vaccines had been exposed to temperatures outside the prescribed range during power cuts. Oral polio vaccine had adequate storage with power cuts of 2 hours' duration.
Alternative facilities for vaccine storage during power cuts were not available and the potency of DPT and measles vaccines were compromised with interruptions to power of 2 hours' duration or more.
研究停电期间EPI疫苗储存的完整性。
科伦坡区的健康中心。
采用访谈式问卷收集工作人员遵守扩大免疫规划(EPI)规定的情况以及停电期间可用的替代冷藏设施的信息。检查了冰箱及其储存条件。给储存的疫苗贴上热敏冷链监测器标签,14天后再次访问诊所时读取监测器数据。在研究期间,每天有持续2小时的停电。在没有停电的情况下进行了对照研究。
白喉-百日咳-破伤风(DPT)疫苗和麻疹疫苗在停电期间暴露于规定温度范围之外。口服脊髓灰质炎疫苗在持续2小时的停电期间储存情况良好。
停电期间没有可用的疫苗储存替代设施,持续2小时或更长时间的停电会损害DPT疫苗和麻疹疫苗的效力。