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Evaluation of growth promotion and inhibition from mycobactins and nonmycobacterial siderophores (Desferrioxamine and FR160) in Mycobacterium aurum.分枝杆菌素和非分枝杆菌铁载体（去铁胺和FR160）对金色分枝杆菌生长促进和抑制作用的评估。
Antimicrob Agents Chemother. 1997 Aug;41(8):1837-9. doi: 10.1128/AAC.41.8.1837.
2
In vitro activity of iron-binding compounds against Senegalese isolates of Plasmodium falciparum.铁结合化合物对塞内加尔恶性疟原虫分离株的体外活性。
J Antimicrob Chemother. 2006 Jun;57(6):1093-9. doi: 10.1093/jac/dkl117. Epub 2006 Apr 4.
3
Effect of microbial siderophores on mammalian non-malignant and malignant cell lines.微生物铁载体对哺乳动物非恶性和恶性细胞系的影响。
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Selective growth promotion and growth inhibition of gram-negative and gram-positive bacteria by synthetic siderophore-beta-lactam conjugates.合成铁载体-β-内酰胺缀合物对革兰氏阴性菌和革兰氏阳性菌的选择性生长促进和生长抑制作用。
Biometals. 1998 Jan;11(1):1-12. doi: 10.1023/a:1009266705308.
5
Characterization of L1210 cell growth inhibition by the bacterial iron chelators parabactin and compound II.细菌铁螯合剂副菌素和化合物II对L1210细胞生长抑制的表征
Cancer Res. 1985 Oct;45(10):4754-9.
6
Siderophore activity of chemically synthesized dihydroxybenzoyl derivatives of spermidines and cystamide.
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Structures of two polyamine-containing catecholate siderophores from Vibrio fluvialis.河流弧菌中两种含多胺儿茶酚型铁载体的结构
J Biochem. 1993 May;113(5):538-44. doi: 10.1093/oxfordjournals.jbchem.a124079.
8
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Biochem Biophys Res Commun. 1984 Jun 29;121(3):848-54. doi: 10.1016/0006-291x(84)90755-1.
9
Biological properties of N4- and N1,N8-spermidine derivatives in cultured L1210 leukemia cells.N4-和N1,N8-亚精胺衍生物在培养的L1210白血病细胞中的生物学特性
Cancer Res. 1985 May;45(5):2050-7.
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Chemical and biological properties of mycobactins isolated from various mycobacteria.从各种分枝杆菌中分离出的分枝菌素的化学和生物学特性。
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Pharmaceuticals (Basel). 2023 Sep 21;16(9):1335. doi: 10.3390/ph16091335.
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Tuning the Anti(myco)bacterial Activity of 3-Hydroxy-4-pyridinone Chelators through Fluorophores.通过荧光团调节3-羟基-4-吡啶酮螯合剂的抗（真菌）细菌活性
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Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents.利用微生物铁同化过程开发新型抗生素并为新型抗癌药物设计提供灵感。
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Siderophore-based iron acquisition and pathogen control.基于铁载体的铁获取与病原体控制。
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Mechanism of Tuberculostasis in Mammalian Serum III. Neutralization of Serum Tuberculostasis by Mycobactin.哺乳动物血清结核抑制作用的机制 III. 分枝菌酸对血清结核抑制作用的中和作用。
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In vitro activities of novel catecholate siderophores against Plasmodium falciparum.新型儿茶酚型铁载体对恶性疟原虫的体外活性
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In vitro antibacterial properties of BRL 36650, a novel 6 alpha-substituted penicillin.新型6α-取代青霉素BRL 36650的体外抗菌特性
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Employment of tuberculostasis in serum-agar medium for the study of production and activity of Mycobactin.在血清琼脂培养基中采用结核菌生长抑制法研究分枝杆菌素的产生及活性。
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分枝杆菌素和非分枝杆菌铁载体（去铁胺和FR160）对金色分枝杆菌生长促进和抑制作用的评估。

Evaluation of growth promotion and inhibition from mycobactins and nonmycobacterial siderophores (Desferrioxamine and FR160) in Mycobacterium aurum.

作者信息

Bosne-David S, Bricard L, Ramiandrasoa F, DeRoussent A, Kunesch G, Andremont A

机构信息

Centro de Malária e outras Doenças Tropicais/IHMT/UNL, Lisbon, Portugal.

出版信息

Antimicrob Agents Chemother. 1997 Aug;41(8):1837-9. doi: 10.1128/AAC.41.8.1837.

DOI:10.1128/AAC.41.8.1837
PMID:9257775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC164019/
Abstract

Heterologous mycobactins and the synthetic FR160 [N4-nonyl,N1,N8-bis(2,3-dihydroxybenzoyl) spermidine hydrobromide (C3 0H4 6N3, O6 Br)] promoted growth in Mycobacterium aurum in low concentrations. They were otherwise highly inhibitory, as opposed to homologous mycobactin, which was strictly growth promoting. Desferrioxamine B (Desferal) had no significant effect on growth.

摘要

异源分枝杆菌素和合成的FR160 [N4-壬基，N1，N8-双(2,3-二羟基苯甲酰基)亚精胺氢溴酸盐(C30H46N3O6Br)]在低浓度下促进了金色分枝杆菌的生长。否则，它们具有高度抑制性，这与严格促进生长的同源分枝杆菌素相反。去铁胺B（去铁敏）对生长没有显著影响。