分枝杆菌素和非分枝杆菌铁载体（去铁胺和FR160）对金色分枝杆菌生长促进和抑制作用的评估。
Evaluation of growth promotion and inhibition from mycobactins and nonmycobacterial siderophores (Desferrioxamine and FR160) in Mycobacterium aurum.
作者信息
Bosne-David S, Bricard L, Ramiandrasoa F, DeRoussent A, Kunesch G, Andremont A
机构信息
Centro de Malária e outras Doenças Tropicais/IHMT/UNL, Lisbon, Portugal.
出版信息
Antimicrob Agents Chemother. 1997 Aug;41(8):1837-9. doi: 10.1128/AAC.41.8.1837.
Abstract
Heterologous mycobactins and the synthetic FR160 [N4-nonyl,N1,N8-bis(2,3-dihydroxybenzoyl) spermidine hydrobromide (C3 0H4 6N3, O6 Br)] promoted growth in Mycobacterium aurum in low concentrations. They were otherwise highly inhibitory, as opposed to homologous mycobactin, which was strictly growth promoting. Desferrioxamine B (Desferal) had no significant effect on growth.
摘要
异源分枝杆菌素和合成的FR160 [N4-壬基，N1，N8-双(2,3-二羟基苯甲酰基)亚精胺氢溴酸盐(C30H46N3O6Br)]在低浓度下促进了金色分枝杆菌的生长。否则，它们具有高度抑制性，这与严格促进生长的同源分枝杆菌素相反。去铁胺B（去铁敏）对生长没有显著影响。
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