Capellaro E, Chiesa A, Villari S, Bontempi S, Sulotto F, Scansetti G
Department of Traumatology, Orthopaedics and Occupational Medicine, University of Turin.
Med Lav. 1997 Mar-Apr;88(2):99-107.
The aim of the study was to determine the concordance of asbestos body (AB) detection in sputum and bronchoalveolar lavage fluid (BALF). AB were detected in the BALF of 110 former or current asbestos workers with medium weak exposure level and, for 65 subjects, in sputum. Several spontaneous sputum samples were taken from each subject. AB prevalence in BALF was rather low (48.2%) especially in subjects with former chrysotile exposure (32.5%). AB prevalence was lower in smokers (40.9%) and ex-smokers (40.7%) than in non-smokers (68.7%). In the sub-group, who underwent both sputum and BALF examination, the concordance of AB detection was observed only in 56.8% of the cases. Neither of the two methods had significant prevalence over the other but were complementary, as both are useful in increasing the probability of AB detection.
本研究的目的是确定痰液和支气管肺泡灌洗液（BALF）中石棉小体（AB）检测结果的一致性。对110名曾经或现在从事石棉工作且接触水平为中度至低度的工人的BALF进行了AB检测，对65名受试者的痰液进行了检测。从每个受试者采集了几份自发痰液样本。BALF中AB的患病率相当低（48.2%），尤其是在既往有温石棉接触史的受试者中（32.5%）。吸烟者（40.9%）和既往吸烟者（40.7%）的AB患病率低于非吸烟者（68.7%）。在同时接受痰液和BALF检查的亚组中，仅56.8%的病例观察到AB检测结果一致。两种方法在患病率上均无显著优势，但具有互补性，因为二者均有助于提高AB检测的概率。
