Van Savage J G, Khoury A E, McLorie G A, Bägli D J
Department of Surgery, Hospital for Sick Children, University of Toronto, Ontario, Canada.
J Urol. 1997 Sep;158(3 Pt 2):1030-2. doi: 10.1097/00005392-199709000-00089.
We present our management algorithm for patients with anterior urethral valves seen in the last 2 decades with and without the benefit of prenatal sonography.
A case series design was used to study 17 cases of anterior urethral valves. Five patients presented with prenatal hydronephrosis from 1984 to 1993 and 12 presented with predominant voiding symptoms between 1975 and 1996 at a mean age of 6 years.
Treatment included supravesical diversion in 1 case, vesicostomy in 5, urethroplasty in 5 and transurethral fulguration in 6. Four of the 5 patients with a prenatal diagnosis of hydronephrosis had moderate to severe hydronephrosis compared to 3 of the 12 who did not undergo prenatal sonography. All 17 patients were continent and infection-free, and had little or no hydronephrosis at a mean followup of 5 years.
We recommend vesicostomy in infants with high grade bilateral vesicoureteral reflux and poor emptying of the urinary tract, transurethral fulguration if the urethra has sufficient caliber and support, and urethroplasty in other patients. Based on our management algorithm patients with anterior urethral valves do not have sequelae due to distal obstruction of the urinary tract.
我们展示了过去20年中诊治前尿道瓣膜患者的管理算法,无论有无产前超声检查的帮助。
采用病例系列设计研究17例前尿道瓣膜患者。1984年至1993年期间,5例患者因产前肾积水就诊,1975年至1996年期间,12例患者主要表现为排尿症状,平均年龄为6岁。
治疗方法包括1例行膀胱上造瘘术、5例行膀胱造瘘术、5例行尿道成形术、6例行经尿道电灼术。产前诊断为肾积水的5例患者中,4例有中度至重度肾积水,而12例未接受产前超声检查的患者中有3例有肾积水。所有17例患者均能自主排尿且无感染,平均随访5年时几乎没有或仅有轻微肾积水。
我们建议,对于患有高度双侧膀胱输尿管反流且尿路排空不良的婴儿行膀胱造瘘术;如果尿道有足够的管径和支撑力,可行经尿道电灼术;其他患者行尿道成形术。根据我们的管理算法,前尿道瓣膜患者不会因尿路远端梗阻而出现后遗症。