Albeck Y
Division of Biology, California Institute of Technology, Pasadena 91125, USA.
Hear Res. 1997 Jul;109(1-2):102-8. doi: 10.1016/s0378-5955(97)00052-x.
In spontaneously active neurons in the external nucleus of the inferior colliculus of the barn owl, a stimulus-driven discharge was followed by a quiescent period lasting tens of milliseconds before the spontaneous activity resumed. The more favorable the interaural time difference, the longer the quiet period. The duration of the quiescent period also depended on stimulus frequency. Frequencies different from the neuron's best frequency induced shorter quiescent periods, although they could elicit similar rates of impulses. Also, the duration of the quiescent period was independent of interaural intensity difference. Thus, the quiet period is not due to an after-hyperpolarization but was an inhibitory effect that depended on the activity of other neurons. In some neurons, discharge continued after the stimulus without a quiescent period and gradually decayed over a period of 50-100 ms past the stimulus offset. The similarity between the quiescent period of the neurons mentioned above and the time course of the poststimulus discharge in these neurons suggests that these neurons serve as inhibitory interneurons.
在仓鸮下丘外侧核的自发活动神经元中，刺激驱动放电之后会有一段持续数十毫秒的静止期，然后才恢复自发活动。双耳时间差越有利，静止期越长。静止期的持续时间也取决于刺激频率。与神经元最佳频率不同的频率会导致较短的静止期，尽管它们能引发相似的冲动发放率。此外，静止期的持续时间与双耳强度差无关。因此，静止期并非由超极化后电位引起，而是一种依赖于其他神经元活动的抑制作用。在一些神经元中，刺激后放电持续且无静止期，并在刺激结束后的50 - 100毫秒内逐渐衰减。上述神经元的静止期与这些神经元刺激后放电的时间进程之间的相似性表明，这些神经元起着抑制性中间神经元的作用。
